Wake Forest University Health Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Wake Forest University Health Sciences sits in the top decile of US sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count).

1,140 total trials 174 currently recruiting 724 completed early-phase tilt top decile by trial count

Wake Forest University Health Sciences: 1,140 sponsored US clinical trials, 174 recruiting.

Wake Forest University Health Sciences sponsors 1,140 registered US clinical trials on ClinicalTrials.gov, 174 of them currently recruiting, and 724 completed. 111 of these trials are in Phase 3-4 (later-stage) and 239 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 9 trials.

Top-decile sponsor footprint

Wake Forest University Health Sciences ranks in the top decile of sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

724 of 885 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,140 total, page 22 of 23

COMPLETED Phase 1

Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

NCT01561014

COMPLETED Phase 2

Vitamin D and Soy Supplements in Treating Patients With Recurrent Prostate Cancer

NCT00499408

COMPLETED Phase 4

The Role of Estrogen in Luteinizing Hormone Surge and Ovulation

NCT01999569

COMPLETED Phase 1

Angiotensin-(1-7) in Treating Patients With Metastatic or Unresectable Solid Tumors

NCT00471562

COMPLETED Phase 1

Intraperitoneal Hyperthermic Perfusion With Oxaliplatin in Treating Patients With Stage IV Peritoneal Cancer Due to Appendix Cancer or Colorectal Cancer

NCT00458809

TERMINATED Phase 3

Soy Protein/Effexor Hormone Therapy for Prostate Cancer

NCT00354432

COMPLETED NA

Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Diseases

NCT00453206

COMPLETED

Reproducibility of 6 Minute Walk Tests for Oxygen Desaturation

NCT00740220

TERMINATED Phase 2

Azacitidine, Darbepoetin Alfa, and Erythropoietin and Filgastrim (G-CSF) in Treating Patients With Myelodysplastic Syndromes

NCT00398047

COMPLETED Phase 2

Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer

NCT01534637

COMPLETED Early Phase 1

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

NCT00452868

COMPLETED

Biomarkers in Patients With Kidney Cancer or Cancer of the Urothelium and in Healthy Participants

NCT00900276

COMPLETED NA

Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases

NCT00376922

COMPLETED Phase 2

Use of Bicarbonate to Reduce the Incidence of Acute Renal Failure After Cardiac Surgery

NCT00484354

COMPLETED Phase 4

Optimizing Body Composition for Function in Older Adults

NCT00315146

TERMINATED Phase 2

St. John's Wort in Relieving Hot Flashes in Postmenopausal Women With Non-Metastatic Breast Cancer

NCT00110136

COMPLETED

Understanding the Genetic and Hereditary Basis of Atherosclerosis

NCT00344292

COMPLETED

Biomarkers in Patients Undergoing Transrectal Ultrasound Prostate Biopsy

NCT00373035

COMPLETED

PET Scans and CT Scans in Patients With Locally Advanced Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy

NCT00388024

COMPLETED NA

Healing Touch in Treating Patients Receiving Chemotherapy for Acute Myeloid Leukemia or Acute Lymphocytic Leukemia

NCT00321880

COMPLETED NA

Improving Employment in Patients Who Have Survived Cervical Cancer, Uterine Cancer, or Ovarian Cancer

NCT00383279

TERMINATED NA

Mirror-Box Training in Adults With Chronic Hemiparesis Secondary to Stroke

NCT00643864

COMPLETED Phase 2

Breath Analysis Technique to Diagnose Pulmonary Embolism

NCT00368836

TERMINATED Phase 2

Docetaxel and Capecitabine in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cavity Cancer

NCT00354601

COMPLETED Phase 4

The Role of Massage in Increasing Total Motile Sperm Count of IUI

NCT01969825

COMPLETED Phase 4

Improving Sleep and Psychological Functioning in People With Depression and Insomnia

NCT00247624

TERMINATED Phase 1

Pemetrexed, Gemcitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

NCT00310050

COMPLETED

Risk Assessment of Long-Haul Truck Drivers

NCT00381992

COMPLETED

Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants

NCT00899496

COMPLETED

Muscle Tissue Bank for Muscular Dystrophy

NCT01950897

COMPLETED NA

Exercise and Weight Loss for Improving Mobility in Older Adults Who Are Obese

NCT00119795

COMPLETED Phase 2

Comparison of Loss of Resistance Techniques

NCT00638274

COMPLETED NA

Written Educational Information and Phone Calls in Increasing Follow-Up Care in Hispanic Women With Abnormal Pap Smears

NCT00483288

COMPLETED NA

Acupressure in Preventing Nausea and Vomiting in Young Cancer Patients Receiving Chemotherapy

NCT00310063

TERMINATED Phase 4

The Efficacy of Crotaline Fab Antivenom for Copperhead Snake Envenomations

NCT00303303

COMPLETED Phase 2

A Phase II Open-Label Study of High-Dose Cytarabine and Clofarabine in Adult Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Refractory or Relapsed Acute Lymphoblastic Leukemia

NCT01656031

COMPLETED Phase 4

Study of Alemtuzumab Versus Anti-thymocyte Globulin to Help Prevent Rejection in Kidney and Pancreas Transplantation

NCT00331162

COMPLETED Phase 1

Cytarabine and Clofarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia

NCT00295841

COMPLETED NA

Soy-Based Meal Replacement in Helping Women With Stage I, Stage II, or Stage III Breast Cancer in Complete Remission Lose Weight

NCT00343434

COMPLETED NA

Policosanol for the Treatment of Hypercholesterolemia

NCT00255216

COMPLETED NA

Ultrasound Guided Arthrocentesis

NCT00537589

TERMINATED Phase 2

Arsenic Trioxide and Cholecalciferol (Vitamin D) in Treating Patients With Myelodysplastic Syndromes

NCT00104806

COMPLETED

Strength and Range of Motion in Women Undergoing Surgery for Breast Cancer

NCT00489125

COMPLETED Phase 2

Clonidine-induced Spinal Acetylcholine Release: Normal Volunteers vs. Neuropathic Pain

NCT00350532

COMPLETED Phase 1

Coenzyme Q10 in Relieving Treatment-Related Fatigue in Women With Breast Cancer

NCT00096356

COMPLETED Phase 2

Clonidine Versus Adenosine to Treat Neuropathic Pain

NCT00349921

COMPLETED

Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors

NCT00499798

TERMINATED

Establishment of a Tissue Bank (Blood, CSF) for the Understanding of Motor Neuron Disease (MND)

NCT01950910

COMPLETED Phase 3

Oxandrolone Compared With Megestrol in Preventing Weight Loss in Patients Receiving Chemotherapy for Cancer

NCT00070148

COMPLETED Phase 3

Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression

NCT00066859

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Phase Distribution

PhaseTrial count
Phase 1 96
Phase 2 143
Phase 3 31
Phase 4 80

What is open in the Wake Forest University Health Sciences pipeline

174 recruiting of 1,140 indexed (15% open); 724 completed (64%).

Phase mix: 111 late (III/IV) vs 239 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Wake Forest University Health Sciences: open-pipeline peers nationwide

Peers matched on 1,140 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share Wake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthUniversity of North Carolina, Chapel HillUniversity of FloridaBaylor UniversityCornell UniversityArrowhead Regional Medical CenterAurinia Pharmaceuticals
Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,140 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Wake Forest University Health Sciences page

1,140 registered trials is a research-attention snapshot, not an endorsement of Wake Forest University Health Sciences or any single study.

  • 174 of Wake Forest University Health Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Wake Forest University Health Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Wake Forest University Health Sciences pipeline card: 1,140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.