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NCT00066859 · ClinicalTrials.gov registry record · Phase 3
Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression
A Phase 3 study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- Phase 3
- Development phase
- 2
- Enrollment target
NCT00066859: Completed Phase 3 study, sponsored by Wake Forest University Health Sciences.
NCT00066859 is a Phase 3 study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 2 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00066859, a Phase 3 study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 2 participants
- Enrollment target
Study Summary
RATIONALE: Antidepressants such as sertraline and the herb hypericum perforatum (St. John's wort) may be effective in treating mild to moderate depression. It is not yet known which treatment is more effective in improving depression in patients who have cancer. PURPOSE: This randomized phase III trial is studying how well sertraline works compared to St. John's wort in treating mild to moderate depression in patients with solid tumors.
Primary Outcome
To compare the change in depression severity in cancer patients with mild to moderate depression on sertraline and St. John's wort.
Interventions
- DRUG Zoloft 50 mg
- DIETARY_SUPPLEMENT St. John's Wort 600 mg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2004-03-01 |
| Est. Completion | 2005-11-01 |
| Phase | Phase 3 |
What the finished NCT00066859 record still lists
NCT00066859 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Zoloft 50 mg is the first listed.
NCT00066859 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00066859 about?
NCT00066859 is a clinical study titled "Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression". RATIONALE: Antidepressants such as sertraline and the herb hypericum perforatum (St. John's wort) may be effective in treating mild to moderate depression. It is not yet known which treatment is more effective in improving depression in patients who have cancer. PURPOSE: This randomized phase III t...
What is the current status of trial NCT00066859?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 2 participants. The study started on 2004-03-01. Estimated completion is 2005-11-01.
What interventions are being tested in trial NCT00066859?
The interventions under investigation include: Zoloft 50 mg (DRUG), St. John's Wort 600 mg (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00066859?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00066859's enrollment target sits among peer trials
2 2000th of 2000 the lowest of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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