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NCT00315146 · ClinicalTrials.gov registry record · Phase 4
Optimizing Body Composition for Function in Older Adults
A Phase 4 study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- Phase 4
- Development phase
- 88
- Enrollment target
NCT00315146: Completed Phase 4 study, sponsored by Wake Forest University Health Sciences.
NCT00315146 is a Phase 4 study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 88 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00315146, a Phase 4 study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 88 participants
- Enrollment target
Study Summary
The purpose of this pilot study is to compare two strategies intended to improve the health of overweight older adults by improving body composition. One strategy, resistance training, is designed to preserve skeletal muscle mass. The other strategy, the use of a PPAR-γ agonist, is designed to enhance the loss of fat from visceral and skeletal depots. These strategies will be used in conjunction with a hypocaloric diet and will be compared to a hypocaloric diet alone to determine if either of these strategies are superior in reducing visceral fat and preserving muscle mass.
Primary Outcome
Change in Appendicular Non-bone Lean Mass
Interventions
- DRUG Placebo
- DRUG Pioglitazone
- BEHAVIORAL Resistance exercise training to maximize muscle power
- BEHAVIORAL Hypocaloric diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2006-04 |
| Est. Completion | 2007-04 |
| Phase | Phase 4 |
What the finished NCT00315146 record still lists
NCT00315146 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 88 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT00315146 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00315146 about?
NCT00315146 is a clinical study titled "Optimizing Body Composition for Function in Older Adults". The purpose of this pilot study is to compare two strategies intended to improve the health of overweight older adults by improving body composition. One strategy, resistance training, is designed to preserve skeletal muscle mass. The other strategy, the use of a PPAR-γ agonist, is designed to enhan...
What is the current status of trial NCT00315146?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 88 participants. The study started on 2006-04. Estimated completion is 2007-04.
What interventions are being tested in trial NCT00315146?
The interventions under investigation include: Placebo (DRUG), Pioglitazone (DRUG), Resistance exercise training to maximize muscle power (BEHAVIORAL), Hypocaloric diet (BEHAVIORAL).
Who is sponsoring clinical trial NCT00315146?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00315146's enrollment target sits among peer trials
88 916th of 2000 higher than 1,078 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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