Wake Forest University Health Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Wake Forest University Health Sciences sits in the top decile of US sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count).

1,140 total trials 174 currently recruiting 724 completed early-phase tilt top decile by trial count

Wake Forest University Health Sciences: 1,140 sponsored US clinical trials, 174 recruiting.

Wake Forest University Health Sciences sponsors 1,140 registered US clinical trials on ClinicalTrials.gov, 174 of them currently recruiting, and 724 completed. 111 of these trials are in Phase 3-4 (later-stage) and 239 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 9 trials.

Top-decile sponsor footprint

Wake Forest University Health Sciences ranks in the top decile of sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

724 of 885 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,140 total, page 21 of 23

COMPLETED Phase 4

A Study Evaluating the Efficacy of Fluocinonide Cream 0.1% (Vanos) in Subjects With Atopic Dermatitis

NCT01049243

COMPLETED NA

Efficacy Evaluation of Observation Unit Cardiac Magnetic Resonance Imaging (MRI) in Patients With Intermediate Risk Acute Chest Pain

NCT00869245

COMPLETED Phase 1

Rapid Administration of Insulin in Sepsis

NCT00823108

COMPLETED

Assessment of Postural Orientation and Equilibrium In Early Amyotrophic Lateral Sclerosis (ALS)

NCT00956501

COMPLETED Phase 1

Phase I Trial of Inhaled Nitric Oxide to Treat Acute Pulmonary Embolism

NCT00848731

COMPLETED NA

Comparison of Three Cannulas for Hysterosalpingography

NCT00956774

COMPLETED Phase 2

High Dose Vitamin D for Sickle Cell Disease

NCT01331148

TERMINATED Phase 2

Laboratory-Treated Autologous Lymphocytes and Aldesleukin After Cyclophosphamide and Fludarabine in Treating Patients With Metastatic Melanoma

NCT00863330

COMPLETED NA

Nipple Sparing Mastectomy - Cosmetic Outcomes

NCT01002014

COMPLETED NA

Early Versus Late Bronchoscopy in Bone Marrow Transplantation (BMT) Patients

NCT00846352

COMPLETED NA

The Teachable Moment: Screening and Brief Intervention for Admitted Trauma Patients

NCT00865774

TERMINATED Early Phase 1

Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR)

NCT00763035

TERMINATED Phase 2

Paricalcitol in Treating Patients With Advanced Prostate Cancer and Bone Metastases

NCT00634582

COMPLETED

Correlation of Oropharyngeal Pepsin and Gastroesophageal (GE) Reflux

NCT01091805

COMPLETED Phase 4

Sexual Absorption of Vaginal Progesterone

NCT01959464

COMPLETED Phase 3

Acyclovir in Preventing Herpes Simplex Virus Infection in Patients With Neutropenia

NCT00855309

COMPLETED

Examining the Relationship Between Hormone Therapy (HT) and Cognitive Function (The WHIMS-ECHO Study)

NCT00745056

COMPLETED Phase 2

American Ginseng Extract in Preventing Respiratory Infection and in Reducing Antibiotic Use in Patients With CLL

NCT00752895

COMPLETED Phase 1

Supported Treadmill Ambulation Training (STAT) for Patients Diagnosed With Amyotrophic Lateral Aclerosis

NCT00956488

COMPLETED Phase 2

Docetaxel, Cisplatin, and Fluorouracil Followed By Cetuximab and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

NCT00721513

COMPLETED

Identification of Diagnostic And Prognostic Biomarkers From Amyotrophic Lateral Sclerosis (ALS) Skin and Adipose Samples

NCT01948102

COMPLETED Phase 1

C-11 Choline PET-CT Scan in Finding Metastases in Patients With Newly Diagnosed High-Risk Prostate Cancer

NCT00804245

COMPLETED NA

Warm Ischemia or Cold Ischemia During Surgery in Treating Patients With Stage I Kidney Cancer

NCT00743236

TERMINATED NA

Aerobic Exercise in Patients Receiving Chemotherapy for Cancer

NCT00728429

COMPLETED NA

Seniors Health and Activity Research Program-Pilot

NCT00688155

TERMINATED Phase 3

Clot Dissolving Treatment for Blood Clots in the Lungs

NCT00680628

COMPLETED Phase 1

Paricalcitol and Chemotherapy in Treating Women With Metastatic Breast Cancer

NCT00637897

COMPLETED

Measuring Stress in Women With Newly Diagnosed Stage I, Stage II, or Stage III Breast Cancer or Ductal Carcinoma In Situ of the Breast

NCT00665782

COMPLETED Early Phase 1

Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery

NCT00601913

COMPLETED NA

Acute Neurobehavioral Program for Improving Functional Status After TBI

NCT01166386

TERMINATED Phase 1

Intensity-Modulated Radiation Therapy, Pemetrexed, and Erlotinib in Treating Patients With Recurrent or Second Primary Head and Neck Cancer

NCT00573989

COMPLETED NA

Carbamazepine for the Treatment of Chronic Post-Traumatic Brain Injury Irritability and Aggression

NCT00621751

COMPLETED

Sex Differences in Vascular Markers of Stroke Risk

NCT00681681

COMPLETED Phase 3

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

NCT00369785

COMPLETED NA

Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain

NCT00678639

COMPLETED NA

Effectiveness Study of a Computer-Based Colorectal Cancer Screening Decision Aid

NCT00558233

COMPLETED

The Effect of Visual Stimuli on Itch Perception Intensity in Healthy and Atopic Dermatitis Patients

NCT00660127

TERMINATED Phase 1

Using Beta Blockers to Treat Mitral Regurgitation

NCT00700947

COMPLETED

Management of Coccydynia: A Prospective, Observational Study of Coccygectomy

NCT02701192

COMPLETED

Coronary Heart Disease as Measured by Coronary Calcium Score Among Individuals With Chronic Traumatic Spinal Cord Injury

NCT00628446

COMPLETED NA

Healthy Living Partnership to Prevent Diabetes

NCT00631345

COMPLETED Phase 2

Docetaxel, Cisplatin, Pegfilgrastim, and Erlotinib Hydrochloride in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

NCT01557959

COMPLETED NA

Physical Activity in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy

NCT00554489

COMPLETED

Using Magnetic Resonance Imaging to Predict People Who Are Likely to Develop Flash Pulmonary Edema (The PREDICT Study)

NCT00542503

COMPLETED NA

Muscadine Grape Seed Supplementation and Vascular Function

NCT01011517

COMPLETED

Physical and Mental Assessment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT00499785

COMPLETED

Non-invasive Blood Pressure (BP) Monitoring Compared to A-Line BP Monitoring

NCT00739700

COMPLETED NA

L-Arginine Supplements in Treating Women Who Are Cancer Survivors

NCT00459134

COMPLETED NA

Radiofrequency Ablation and External-Beam Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

NCT00499447

TERMINATED

Tamoxifen Resistance in Women With Stage I, Stage II, Stage IIIA, or Stage IIIB Breast Cancer

NCT00899197

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Phase Distribution

PhaseTrial count
Phase 1 96
Phase 2 143
Phase 3 31
Phase 4 80

What is open in the Wake Forest University Health Sciences pipeline

174 recruiting of 1,140 indexed (15% open); 724 completed (64%).

Phase mix: 111 late (III/IV) vs 239 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Wake Forest University Health Sciences: open-pipeline peers nationwide

Peers matched on 1,140 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share Wake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthUniversity of North Carolina, Chapel HillUniversity of FloridaBaylor UniversityCornell UniversityArrowhead Regional Medical CenterAurinia Pharmaceuticals
Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,140 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Wake Forest University Health Sciences page

1,140 registered trials is a research-attention snapshot, not an endorsement of Wake Forest University Health Sciences or any single study.

  • 174 of Wake Forest University Health Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Wake Forest University Health Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Wake Forest University Health Sciences pipeline card: 1,140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.