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NCT00823108 · ClinicalTrials.gov registry record · Phase 1
Rapid Administration of Insulin in Sepsis
A Phase 1 study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT00823108: Completed Phase 1 study, sponsored by Wake Forest University Health Sciences.
NCT00823108 is a Phase 1 study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00823108, a Phase 1 study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if a glucose-insulin-potassium (GIK) solution can be safely administered to patients with septic shock. GIK has been used in thousands of critically ill patients in research studies with very few safety concerns. However, there is a lack of data in regards to patients with septic shock. There are many reasons to believe that GIK would be beneficial in sepsis, including improving heart function and decreasing inflammation. This study will administer intravenous GIK for 12 hours continuously and monitor 10 subjects for 24 hours. A control arm will be used and 10 patients will receive the same monitoring but will not receive GIK.
Interventions
- DRUG GIK
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2009-03 |
| Est. Completion | 2010-10 |
| Phase | Phase 1 |
What the finished NCT00823108 record still lists
NCT00823108 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 1 intervention - of which GIK is the first listed.
NCT00823108 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00823108 about?
NCT00823108 is a clinical study titled "Rapid Administration of Insulin in Sepsis". The purpose of this study is to determine if a glucose-insulin-potassium (GIK) solution can be safely administered to patients with septic shock. GIK has been used in thousands of critically ill patients in research studies with very few safety concerns. However, there is a lack of data in regards t...
What is the current status of trial NCT00823108?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2009-03. Estimated completion is 2010-10.
What interventions are being tested in trial NCT00823108?
The interventions under investigation include: GIK (DRUG).
Who is sponsoring clinical trial NCT00823108?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00823108's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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