Wake Forest University Health Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Wake Forest University Health Sciences sits in the top decile of US sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count).

1,140 total trials 174 currently recruiting 724 completed early-phase tilt top decile by trial count

Wake Forest University Health Sciences: 1,140 sponsored US clinical trials, 174 recruiting.

Wake Forest University Health Sciences sponsors 1,140 registered US clinical trials on ClinicalTrials.gov, 174 of them currently recruiting, and 724 completed. 111 of these trials are in Phase 3-4 (later-stage) and 239 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 9 trials.

Top-decile sponsor footprint

Wake Forest University Health Sciences ranks in the top decile of sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

724 of 885 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,140 total, page 20 of 23

COMPLETED Phase 2

A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas

NCT01188096

COMPLETED NA

Distal Locking Using an Electromagnetic Field Guided Computer Based Real Time System for Orthopaedic Trauma Patients

NCT01183078

TERMINATED Phase 1

Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery

NCT01197664

COMPLETED NA

Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery

NCT01167907

COMPLETED NA

Lactation Education Study in Mothers of Very Low Birth Weight Infants

NCT01167517

COMPLETED NA

Combination Gel and Vascular ND in Mild to Moderate Rosacea

NCT01631656

COMPLETED Phase 2

Omegaven® in the Treatment of Parenteral Nutrition (PN) Induced Liver Injury

NCT01845116

COMPLETED NA

Transoral Robotic Surgery (TORS) for Oral and Laryngopharyngeal Lesions Using Da Vinci Robotic Surgical System

NCT01059357

COMPLETED NA

Breast Cancer Rehabilitation Program in Improving Quality of Life in Breast Cancer Survivors

NCT01113554

COMPLETED

Idiopathic Recurrent Acute Pancreatitis (IRAP)

NCT01133535

COMPLETED Early Phase 1

Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates

NCT01314742

COMPLETED NA

Building Social Networks to Enhance Postpartum Weight Loss and Appropriate Infant Feeding Practices

NCT01081340

COMPLETED NA

Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

NCT01126346

COMPLETED NA

Intraosseous Versus Intravenous Vascular Access During Cardiac Arrest

NCT01119807

TERMINATED Phase 1

Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma

NCT01103375

COMPLETED NA

Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer

NCT01053494

COMPLETED Phase 1

A Pilot C11-Choline PET-CT Imaging Study in Patients With Locally Advanced Esophageal Cancer

NCT01051479

COMPLETED Phase 1

Study to Evaluate Safety, Tolerability, Maximum Tolerated Dose (MTD), Efficacy, and Pharmacokinetics (PKs) of CPI-613 Given Twice Weekly for Three Consecutive Weeks in Patients With Advanced Hematologic Malignancies

NCT01034475

TERMINATED Phase 2

Paclitaxel, Carboplatin, and Panitumumab in Treating Patients With Metastatic Breast Cancer

NCT01009983

COMPLETED

Physical Activity, Weight and Fitness Outcomes in Children in After-Care

NCT01063413

TERMINATED NA

Thermal Ablation Combined With External Beam Radiation Therapy for Patients With Inoperable Non-Small Cell Lung Cancer > 3.5 cm in Size

NCT01028612

TERMINATED

Patient Registry: Partial Breast Irradiation

NCT01127971

COMPLETED NA

Translating Dietary Trials Into the Community

NCT00964483

COMPLETED NA

Yoga or Educational Wellness Class for Women With Stage I, Stage II, or Stage III Breast Cancer Undergoing Chemotherapy

NCT00994279

COMPLETED Early Phase 1

Vitamin D Supplementation and Physical Function in Older Adults

NCT01179503

COMPLETED NA

Randomized Investigation of Chest Pain Diagnostic Strategies

NCT01035047

COMPLETED NA

Assessment of Acute Disease to Reduce Imaging Costs

NCT01059500

COMPLETED

Frailty Index and Geriatric Assessment in Predicting Toxicity to Front-Line Chemotherapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer

NCT01026467

COMPLETED NA

Nurse Education in Subjects With Psoriasis Undergoing Treatment With Adalimumab

NCT01435265

TERMINATED Phase 1

Rosuvastatin in Treating Women With Cardiovascular Complications Who Are Undergoing Chemotherapy For Breast Cancer

NCT01051401

COMPLETED NA

Do Motion Metrics Lead to Improved Skill Acquisition on Simulators?

NCT01052168

COMPLETED Phase 2

Therapeutic Angiotensin-(1-7) in Treating Patients With Metastatic Sarcoma That Cannot Be Removed By Surgery

NCT01553539

COMPLETED

Prevalence of Sleep Disturbances in Psoriasis

NCT00895375

COMPLETED NA

Pulsed Dye Laser in Treating Patients With Post Radiation Dysphonia

NCT02198131

COMPLETED NA

Investigating Fitness Interventions in the Elderly (INFINITE)

NCT01048736

COMPLETED

Dietary Patterns and Cardiovascular (CVD) Risk in Spinal Cord Injury (SCI) Factors In Individuals With Chronic Spinal Cord Injury

NCT01025609

COMPLETED NA

Reusable Versus Disposable Draping System in Breast Reconstruction Surgery

NCT01176786

COMPLETED Phase 4

Comparing Aquaphor to Atopiclair and EpiCeram in Children With Mild to Moderate Atopic Dermatitis

NCT01093469

TERMINATED Phase 4

Dysfunctional Voiding and Lower Urinary Tract Symptoms With Baclofen

NCT01003249

COMPLETED NA

Amantadine for the Treatment of Traumatic Brain Injury Irritability and Aggression: A Multi-site Study

NCT00779324

COMPLETED NA

A Comparison of Different Ventilation Strategies in Children Using the Proseal™ Laryngeal Mask Airway

NCT00966433

TERMINATED Phase 2

Combined Spinal/Epidural (CSE) Saline Duration/Spread

NCT01062893

TERMINATED Phase 1

Donor Lymphocyte Infusion After Alternative Donor Transplantation

NCT01027702

TERMINATED Phase 2

T-cell Depleted Alternative Donor Transplantation

NCT00968864

COMPLETED Phase 4

Effects of Aliskiren on Patient With Heart Failure and a Normal Ejection Fraction

NCT00982033

COMPLETED

Memory Study of Youngest Women Enrolled in the Women's Health Initiative Hormone Therapy (HT) Arm

NCT01124773

TERMINATED NA

Dual Site Left Ventricular (LV) Pacing

NCT00944125

COMPLETED Phase 2

Surgery and Oxaliplatin or Mitomycin C in Treating Patients With Tumors of the Appendix

NCT01580410

COMPLETED Phase 2

Botanical Oil Supplementation in Diabetic and Metabolic Syndrome Subjects

NCT01145066

TERMINATED NA

Yoga in Relieving Fatigue in Patients Undergoing Chemotherapy for Ovarian Cancer

NCT00856453

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Phase Distribution

PhaseTrial count
Phase 1 96
Phase 2 143
Phase 3 31
Phase 4 80

What is open in the Wake Forest University Health Sciences pipeline

174 recruiting of 1,140 indexed (15% open); 724 completed (64%).

Phase mix: 111 late (III/IV) vs 239 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Wake Forest University Health Sciences: open-pipeline peers nationwide

Peers matched on 1,140 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share Wake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthUniversity of North Carolina, Chapel HillUniversity of FloridaBaylor UniversityCornell UniversityArrowhead Regional Medical CenterAurinia Pharmaceuticals
Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,140 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Wake Forest University Health Sciences page

1,140 registered trials is a research-attention snapshot, not an endorsement of Wake Forest University Health Sciences or any single study.

  • 174 of Wake Forest University Health Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Wake Forest University Health Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Wake Forest University Health Sciences pipeline card: 1,140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.