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NCT01059500 · ClinicalTrials.gov registry record · NA

Assessment of Acute Disease to Reduce Imaging Costs

A NA study, sponsored by Wake Forest University Health Sciences.

Completed
Registry status
NA
Development phase
550
Enrollment target

NCT01059500: Completed NA study, sponsored by Wake Forest University Health Sciences.

NCT01059500 is a NA study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 550 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (61% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01059500, a NA study, has completed, sponsored by Wake Forest University Health Sciences.

COMPLETED
Registry status
NA
Development phase
550 participants
Enrollment target

Study Summary

Overtesting for Acute Coronary Syndrome(ACS) and Pulmonary Embolism (PE) in low risk Emergency Department(ED) patients can increase exposure of nondiseased patients to radiation, intravenous contrast and anticoagulation. This project addresses question of whether quantitative Pre-Test Probability(PTP) assessed from two validated web-based computer algorithms (the project "webtool"), can improve the diagnostic evaluation of adult patients with charted evidence of chest pain and dyspnea. After a validation phase, the main study will randomize patients to either the Standard care group or the Intervention group, which will receive the output of the ACS and PE webtool that includes the PTP estimates of ACS and PE and one of three recommendations regarding next steps: 1. No further testing, 2. Exclusion with a biomarker protocol, or 3. Immediate imaging +/- empiric anticoagulation.

Primary Outcome

Only costs at the enrollment hospital will be used, and only for patients who indicate that they did not visit any other hospital at the time of phone follow-up. Costs would exclude unexpected and unrelated events such as trauma. Additionally, estimated costs associated with the time required of the clinician to gather and enter the 17 variables are included.

Interventions

  • DEVICE Webtool

Trial Details

FieldValue
Enrollment Target 550 participants
Start Date 2010-01
Est. Completion 2013-02
Phase NA
Wake Forest University Health Sciences

1,140 total trials

What the finished NCT01059500 record still lists

NCT01059500 is an interventional study that assigns participants to a tested intervention. The registered 550 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (61% lower).

The record links to 0 conditions, and to 1 intervention - of which Webtool is the first listed.

NCT01059500 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01059500 about?

NCT01059500 is a clinical study titled "Assessment of Acute Disease to Reduce Imaging Costs". Overtesting for Acute Coronary Syndrome(ACS) and Pulmonary Embolism (PE) in low risk Emergency Department(ED) patients can increase exposure of nondiseased patients to radiation, intravenous contrast and anticoagulation. This project addresses question of whether quantitative Pre-Test Probability(PT...

What is the current status of trial NCT01059500?

This trial is currently completed. It is a NA study. The enrollment target is 550 participants. The study started on 2010-01. Estimated completion is 2013-02.

What interventions are being tested in trial NCT01059500?

The interventions under investigation include: Webtool (DEVICE).

Who is sponsoring clinical trial NCT01059500?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01059500's enrollment target sits among peer trials

550 184th of 2000 higher than 1,815 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01059500, the US trial registry maintained by the National Library of Medicine. NCT01059500 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.