Wake Forest University Health Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Wake Forest University Health Sciences sits in the top decile of US sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count).

1,140 total trials 174 currently recruiting 724 completed early-phase tilt top decile by trial count

Wake Forest University Health Sciences: 1,140 sponsored US clinical trials, 174 recruiting.

Wake Forest University Health Sciences sponsors 1,140 registered US clinical trials on ClinicalTrials.gov, 174 of them currently recruiting, and 724 completed. 111 of these trials are in Phase 3-4 (later-stage) and 239 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 9 trials.

Top-decile sponsor footprint

Wake Forest University Health Sciences ranks in the top decile of sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

724 of 885 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,140 total, page 16 of 23

TERMINATED NA

Reducing Lung Cancer-Related Anxiety (RELAX)

NCT02063828

COMPLETED

Human Prostate Tissue Model to Maintain and Study Prostate Cancer Stem Cells

NCT02425800

COMPLETED NA

A Trial of RSL Versus WL for Malignant Breast Disease

NCT02522468

COMPLETED NA

Impact of Skin to Skin Contact on Maternal Satisfaction, Pain Scores, and Narcotic Usage After Cesarean Delivery

NCT02533167

COMPLETED Phase 4

Perineural Steroids for Peripheral Nerve Blocks

NCT02462148

COMPLETED

MICU Recovery Clinic

NCT02560129

COMPLETED NA

Biodistribution of [11C]Acetoacetate/[18F]Fluorodeoxyglucose in Subjects With Risk Factors for Alzheimer's Disease

NCT03130036

TERMINATED Phase 2

Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

NCT02337478

TERMINATED NA

Do Peanut Shaped Birthing Balls Reduce the Length of Labor in Patients With Epidural Analgesia?

NCT02539563

COMPLETED NA

Strength Testing After Nitrate Delivery (STAND) in ICU Patients

NCT02293616

COMPLETED Phase 4

Systemic Steroids for Peripheral Nerve Blocks

NCT02464176

COMPLETED

Motor Development of Children That Have Surgery as Newborns for Complex Congenital Heart Disease

NCT02781545

COMPLETED Phase 2

Pemetrexed Disodium in Treating Patients With Stage IV Non-small Cell Lung Cancer and ECOG Performance Status 3

NCT02426658

COMPLETED NA

Improving Resection Rates Among African Americans With NSCLC

NCT01885455

COMPLETED

Operative and Non-operative Treatment of Traumatic Arthrotomies

NCT02841644

COMPLETED Phase 1

Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart

NCT02462161

COMPLETED NA

Website Application Based Education and Text Messaging in Improving Skin Wound Care in Patients Undergoing Mohs Surgery

NCT02373722

COMPLETED NA

Consumer-Based Activity Monitor in Evaluating and Measuring Activity of Older Patients With Abdominal Cancer Undergoing Surgery

NCT02356471

COMPLETED Phase 2

Donor Stem Cell Transplant Followed by Cyclophosphamide in Treating Patients With Hematological Diseases

NCT02248597

COMPLETED NA

HIRREM in Military Personnel

NCT03230890

COMPLETED NA

Nutrition Education for Cardiovascular Disease Prevention in Spinal Cord Injury

NCT02368405

COMPLETED NA

Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease

NCT02984540

TERMINATED

Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation Therapy

NCT02375334

TERMINATED Phase 4

Cilostazol After Lower Extremity Arterial Revascularization Trial

NCT02374957

COMPLETED Phase 1

CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

NCT02232152

COMPLETED

Goal-directed Fluid Therapy on Complications After Pancreaticoduodenectomy

NCT03699917

TERMINATED Phase 2

A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)

NCT02343549

COMPLETED

Study of the Immune Response After Vaccination in Multiple Myeloma Patients

NCT02294487

COMPLETED Phase 2

Qsymia as an Adjunct to Surgical Therapy in the Superobese

NCT02301416

COMPLETED

Evaluation of Loratadine for G-CSF Induced Bone Pain in Patients With Hematologic Malignancies

NCT02305979

COMPLETED Phase 1

APN401 in Treating Patients With Melanoma, Kidney Cancer, Pancreatic Cancer, or Other Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery

NCT02166255

COMPLETED Phase 2

LCI-LUN-ABR-001: Carbo With Nab-Paclitaxel in Patients With Advanced NSCL Cancer

NCT02328105

COMPLETED Phase 4

Intravesicular Onabotulinumtoxin A in Interstitial Cystitis

NCT02297100

COMPLETED Phase 4

Spironolactone After Liver Transplant

NCT02883400

COMPLETED

Cutaneous Lupus Medication Experience Study

NCT02176148

TERMINATED Phase 1

CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

NCT02168907

COMPLETED NA

Project 1, Study 2: The Combined Impact of Nicotine Replacement and Spectrum Cigarettes

NCT02301325

COMPLETED Phase 2

Botulinum Toxin for the Management of Chronic Orchialgia

NCT02058836

COMPLETED NA

Glioma Modified Atkins-based Diet in Patients With Glioblastoma

NCT02286167

COMPLETED NA

Arthritis Pilot for Preserving Muscle While Losing Weight

NCT02239939

COMPLETED Early Phase 1

A Pilot Study to Examine the Effects of Vitamin D Supplementation on Mitochondrial Bioenergetics in Older Adults

NCT02445066

COMPLETED

Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome

NCT02265198

COMPLETED NA

A Trial of Rehabilitation Therapy in Older Acute Heart Failure Patients

NCT02196038

COMPLETED NA

Project 2: Strategies for Reducing Nicotine Content in Cigarettes

NCT02139930

COMPLETED

Attention Deficit/Hyperactivity Disorder Internet Survey Study in a College Student Population

NCT02251080

COMPLETED Phase 1

CPI-613 and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma

NCT02168140

COMPLETED NA

Be a Champion! Comprehensive School Physical Activity Program

NCT02465372

COMPLETED

Evaluation of Minimally Invasive Subcortical Parafascicular Access for Clot Evacuation

NCT02331719

COMPLETED

Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK)

NCT03317925

COMPLETED

Communication Effectiveness in Cancer Treatment

NCT02197091

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Phase Distribution

PhaseTrial count
Phase 1 96
Phase 2 143
Phase 3 31
Phase 4 80

What is open in the Wake Forest University Health Sciences pipeline

174 recruiting of 1,140 indexed (15% open); 724 completed (64%).

Phase mix: 111 late (III/IV) vs 239 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Wake Forest University Health Sciences: open-pipeline peers nationwide

Peers matched on 1,140 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share Wake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthUniversity of North Carolina, Chapel HillUniversity of FloridaBaylor UniversityCornell UniversityArrowhead Regional Medical CenterAurinia Pharmaceuticals
Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,140 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Wake Forest University Health Sciences page

1,140 registered trials is a research-attention snapshot, not an endorsement of Wake Forest University Health Sciences or any single study.

  • 174 of Wake Forest University Health Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Wake Forest University Health Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Wake Forest University Health Sciences pipeline card: 1,140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.