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NCT03317925 · ClinicalTrials.gov registry record
Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK)
A clinical trial of Renal Transplant and Rejection Chronic Renal, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- 29
- Enrollment target
- 1
- Study location
NCT03317925: Completed study of Renal Transplant and Rejection Chronic Renal, sponsored by Wake Forest University Health Sciences.
NCT03317925 is a study of Renal Transplant and Rejection Chronic Renal that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 29 participants, below the 46-participant average among 5 other Renal Transplant trials with a reported enrollment target (37% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03317925, a study of Renal Transplant and Rejection Chronic Renal, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- 29 participants
- Enrollment target
- 1
- Study location
Study Summary
In pediatric kidney transplant patients, rejection, medication toxicity and ischemia cause early and chronic renal allograft injury, which reduces graft lifespan and patient survival. Early detection of injury would facilitate prevention and treatment. The gold standard surveillance biopsy has limitations including delayed discovery of injury. No noninvasive test identifies graft injury before it is clinically apparent. This project's goal is to develop a novel early marker of subclinical graft injury to facilitate prompt recognition and treatment.
Primary Outcome
Renal biopsy-confirmed acute renal allograft injury as determined by a pathologist (binary yes or no)
Conditions Studied
Interventions
- PROCEDURE Renal Transplantation
Study Locations (1)
North Carolina
- Wake Forest University Baptist Medical Center - Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2014-07-16 |
| Est. Completion | 2017-04-26 |
What the finished NCT03317925 record still lists
NCT03317925 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 46-participant average among 5 other Renal Transplant trials with a reported enrollment target (37% lower).
The record links to 5 conditions, with Renal Transplant appearing as the primary indexed condition, and to 1 intervention - of which Renal Transplantation is the first listed.
NCT03317925 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT03317925 about?
NCT03317925 is a clinical study titled "Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK)". In pediatric kidney transplant patients, rejection, medication toxicity and ischemia cause early and chronic renal allograft injury, which reduces graft lifespan and patient survival. Early detection of injury would facilitate prevention and treatment. The gold standard surveillance biopsy has limit...
What is the current status of trial NCT03317925?
This trial is currently completed. The enrollment target is 29 participants. The study started on 2014-07-16. Estimated completion is 2017-04-26.
What conditions does trial NCT03317925 study?
This clinical trial studies the following conditions: Renal Transplant, Rejection Chronic Renal, Renin-Angiotensin System, Rejection Acute Renal, Rejection of Renal Transplant.
What interventions are being tested in trial NCT03317925?
The interventions under investigation include: Renal Transplantation (PROCEDURE).
Who is sponsoring clinical trial NCT03317925?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03317925 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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