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NCT02139930 · ClinicalTrials.gov registry record · NA

Project 2: Strategies for Reducing Nicotine Content in Cigarettes

A NA study, sponsored by Wake Forest University Health Sciences.

Completed
Registry status
NA
Development phase
1,250
Enrollment target

NCT02139930: Completed NA study, sponsored by Wake Forest University Health Sciences.

NCT02139930 is a NA study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 1,250 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (11% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02139930, a NA study, has completed, sponsored by Wake Forest University Health Sciences.

COMPLETED
Registry status
NA
Development phase
1,250 participants
Enrollment target

Study Summary

The main goal of this project is to compare two different approaches to reducing levels of nicotine in cigarettes: an immediate reduction in nicotine content in cigarettes to non-addictive levels or a gradual reduction in nicotine content in cigarettes to non-addictive levels. These two approaches will then be contrasted to a group that continues to smoke cigarettes with nicotine content similar to conventional cigarettes.

Primary Outcome

Between group comparison of expired air carbon monoxide (CO) values at week 20 using baseline CO values as a covariate.

Interventions

  • BEHAVIORAL Normal Nicotine Control Group
  • BEHAVIORAL Immediate Nicotine Reduction Group
  • BEHAVIORAL Gradual Nicotine Reduction Group

Trial Details

FieldValue
Enrollment Target 1,250 participants
Start Date 2014-09
Est. Completion 2017-03-14
Phase NA
Wake Forest University Health Sciences

1,140 total trials

What the finished NCT02139930 record still lists

NCT02139930 is an interventional study that assigns participants to a tested intervention. Its 1,250 participants enrollment target places it among the larger protocols in the corpus, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (11% lower).

The record links to 0 conditions, and to 3 interventions - of which Normal Nicotine Control Group is the first listed.

NCT02139930 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02139930 about?

NCT02139930 is a clinical study titled "Project 2: Strategies for Reducing Nicotine Content in Cigarettes". The main goal of this project is to compare two different approaches to reducing levels of nicotine in cigarettes: an immediate reduction in nicotine content in cigarettes to non-addictive levels or a gradual reduction in nicotine content in cigarettes to non-addictive levels. These two approaches w...

What is the current status of trial NCT02139930?

This trial is currently completed. It is a NA study. The enrollment target is 1,250 participants. The study started on 2014-09. Estimated completion is 2017-03-14.

What interventions are being tested in trial NCT02139930?

The interventions under investigation include: Normal Nicotine Control Group (BEHAVIORAL), Immediate Nicotine Reduction Group (BEHAVIORAL), Gradual Nicotine Reduction Group (BEHAVIORAL).

Who is sponsoring clinical trial NCT02139930?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02139930's enrollment target sits among peer trials

1,250 80th of 2000 higher than 1,919 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02139930, the US trial registry maintained by the National Library of Medicine. NCT02139930 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.