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NCT02462161 · ClinicalTrials.gov registry record · Phase 1
Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart
A Phase 1 study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT02462161: Completed Phase 1 study, sponsored by Wake Forest University Health Sciences.
NCT02462161 is a Phase 1 study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02462161, a Phase 1 study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
This pilot clinical trial will examine the effects of intranasal insulin aspart on cognition, daily function, blood and cerebral spinal fluid markers of Alzheimer's disease, and amyloid deposition in the brain. Participants will be randomly assigned to receive insulin aspart or placebo during a 12-week treatment period.
Primary Outcome
Alzheimer's Disease Assessment Scale-Cognitive Subscale(ADAS-Cog)/mild cognitive impairment (MCI) scores and memory composite (summed Z scores from delayed story and list recall)
Interventions
- DRUG Placebo
- DRUG Insulin aspart
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2015-03-20 |
| Est. Completion | 2019-04-16 |
| Phase | Phase 1 |
What the finished NCT02462161 record still lists
NCT02462161 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02462161 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02462161 about?
NCT02462161 is a clinical study titled "Study of Nasal Insulin to Fight Forgetfulness - Short-Acting Insulin Aspart". This pilot clinical trial will examine the effects of intranasal insulin aspart on cognition, daily function, blood and cerebral spinal fluid markers of Alzheimer's disease, and amyloid deposition in the brain. Participants will be randomly assigned to receive insulin aspart or placebo during a 12-w...
What is the current status of trial NCT02462161?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2015-03-20. Estimated completion is 2019-04-16.
What interventions are being tested in trial NCT02462161?
The interventions under investigation include: Placebo (DRUG), Insulin aspart (DRUG).
Who is sponsoring clinical trial NCT02462161?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02462161's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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