Wake Forest University Health Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Wake Forest University Health Sciences sits in the top decile of US sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count).

1,140 total trials 174 currently recruiting 724 completed early-phase tilt top decile by trial count

Wake Forest University Health Sciences: 1,140 sponsored US clinical trials, 174 recruiting.

Wake Forest University Health Sciences sponsors 1,140 registered US clinical trials on ClinicalTrials.gov, 174 of them currently recruiting, and 724 completed. 111 of these trials are in Phase 3-4 (later-stage) and 239 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 9 trials.

Top-decile sponsor footprint

Wake Forest University Health Sciences ranks in the top decile of sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

724 of 885 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,140 total, page 13 of 23

COMPLETED NA

Use of a Self-Directed Exercise Program (SDEP) Following Selected Lower Extremity Fractures

NCT04612478

COMPLETED

Work Ability in Young Adult Cancer Survivors

NCT03148080

TERMINATED NA

Efficacy of a Recreation Therapy Wellness Recovery Program for Individuals With Parkinson's Disease

NCT04164043

COMPLETED Phase 4

Pain Control in Colorectal Surgery: Liposomal Bupivacaine Block Versus Intravenous Lidociane

NCT04005859

COMPLETED

Health Outcomes After Participating in Exercise (HOPE)

NCT03430115

COMPLETED

Measuring Health Related Quality of Life in AYAs

NCT03482778

COMPLETED NA

Improvisational Movement for People With Memory Loss and Their Caregivers

NCT03333837

TERMINATED Phase 2

The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems

NCT03716050

COMPLETED NA

EZ-blocker Versus Left Sided Double Lumen Tube in Adult Patients for Thoracic Surgery

NCT03403192

COMPLETED NA

LCI-GER-NOS-TAB-001: Tablet for Geriatric Assessment

NCT03419468

COMPLETED Phase 2

LCI-HEM-MYE-CRD-002: Carfilzomib-Revlimid-Dexamethasone-Elotuzumab in Relapsed/Refractory Multiple Myeloma

NCT03361306

COMPLETED

Does Modified Ultrafiltration Affect Thromboelastography Results?

NCT03214120

COMPLETED NA

Apneic Oxygenation in the Pediatric Intensive Care Unit

NCT03374046

COMPLETED

Trauma Routing Algorithm for Pediatrics

NCT03359421

COMPLETED NA

Cognitive Dysfunction and Breast Cancer Coping Strategies Impact on QOL

NCT03476226

COMPLETED NA

Interactive Group Drumming (IGD) in Hospital Experience of Patients Undergoing Hematopoietic Stem Cell Transplant - A Pilot Study

NCT03345433

COMPLETED NA

Healthy Living Partnerships to Prevent Diabetes in Veterans Pilot Study

NCT02835495

TERMINATED Phase 2

LCI-GI-APX-NIN-001: Nintedanib in Metastatic Appendiceal Carcinoma

NCT03287947

TERMINATED Phase 4

Residual Anti-Xa Activity After Last Treatment Dose of Enoxaparin

NCT03296033

COMPLETED NA

Rivanna Ultrasound for Neuraxial Block

NCT03214640

COMPLETED

Brilliant Study: Assessing Cognition in Myeloma Patients Undergoing Transplant

NCT03355235

COMPLETED NA

Mediterranean Diet and the Gut Microbiome

NCT03269032

TERMINATED Phase 4

Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)

NCT03219866

COMPLETED Phase 1

Eucrisa for Atopic Dermatitis

NCT03250663

COMPLETED

Food Security and Perceptions and Barriers to Healthy Eating in Individuals With Spinal Cord Injuries

NCT03457558

COMPLETED

Correcting Platelet Dysfunction After Traumatic Brain Injury

NCT03182946

COMPLETED Phase 4

Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery

NCT03287089

COMPLETED NA

Virtual Seating Coach on Power Wheelchairs of Persons With Amyotrophic Lateral Sclerosis (ALS)

NCT05742828

TERMINATED

Pediatric Hypertension Registry (PHREG)

NCT03305562

COMPLETED

Is Tau Protein Linked to Mobility Function?

NCT03430648

COMPLETED Phase 2

Harvoni Treatment Porphyria Cutanea Tarda

NCT03118674

COMPLETED NA

Virtual Visits (Utilization of Virtual Care in Postoperative Patients to Improve the Patient Experience)

NCT03258177

COMPLETED NA

Patient Management of Depression Through Technology: a Study of Digitally Enabled Engagement

NCT03242213

COMPLETED NA

HELP Prevent Cancer Pilot Study

NCT02960542

COMPLETED NA

Healthy Weight Poster, Multi-site Study

NCT03128112

COMPLETED

TS Overexpression in SCLC: Mechanism and Therapeutic Targeting

NCT03741829

COMPLETED Phase 2

Pilot Study of Paclitaxel Plus Pembrolizumab in Metastatic HER2-Negative Breast Cancer

NCT03018080

COMPLETED NA

An Evaluation of Post Discharge Utilization Among Patients With an Acute Exacerbation of COPD

NCT03207776

COMPLETED NA

Evaluation of Behavioral Health-Virtual Patient Navigation Team (BH-VPN)

NCT03204643

TERMINATED NA

Comparison of EVD Catheter Diameter on Occlusion and Replacement

NCT03248739

COMPLETED Early Phase 1

PECS Block: Plasma Bupivacaine Level

NCT03059498

COMPLETED NA

Assessing Patient Confidence in Biologic Medications

NCT03168347

COMPLETED

Postop Pain in the MICS Patients Versus Sternotomy Patients

NCT04003584

COMPLETED Phase 3

Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil

NCT02822573

COMPLETED NA

A Study Promoting Critical Illness Recovery in the Elderly

NCT02963558

COMPLETED NA

Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck Cancer

NCT03032250

COMPLETED NA

Ultrasound in Detecting Taxane-Induced Neuropathy in Patients With Breast Cancer

NCT03139435

COMPLETED NA

Prospective Evaluation of 14F Thal Tube vs 28 French Chest Tube for Hemothorax and Use of Maximum Barrier Precautions

NCT03167723

COMPLETED NA

Utilizing Protein During Weight Loss to Impact Physical Function

NCT03074643

COMPLETED NA

Utilizing Protein During Weight Loss to Impact Physical Function and Bone

NCT03819478

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Phase Distribution

PhaseTrial count
Phase 1 96
Phase 2 143
Phase 3 31
Phase 4 80

What is open in the Wake Forest University Health Sciences pipeline

174 recruiting of 1,140 indexed (15% open); 724 completed (64%).

Phase mix: 111 late (III/IV) vs 239 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Wake Forest University Health Sciences: open-pipeline peers nationwide

Peers matched on 1,140 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share Wake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthUniversity of North Carolina, Chapel HillUniversity of FloridaBaylor UniversityCornell UniversityArrowhead Regional Medical CenterAurinia Pharmaceuticals
Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,140 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Wake Forest University Health Sciences page

1,140 registered trials is a research-attention snapshot, not an endorsement of Wake Forest University Health Sciences or any single study.

  • 174 of Wake Forest University Health Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Wake Forest University Health Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Wake Forest University Health Sciences pipeline card: 1,140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.