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NCT03219866 · ClinicalTrials.gov registry record · Phase 4

Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)

A Phase 4 study, sponsored by Wake Forest University Health Sciences.

Terminated
Registry status
Phase 4
Development phase
40
Enrollment target

NCT03219866 is a Phase 4 study that was terminated before completion, run by Wake Forest University Health Sciences. The registered enrollment target is 40 participants.

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The verdict

NCT03219866, a Phase 4 study, was terminated before completion, sponsored by Wake Forest University Health Sciences.

TERMINATED
Registry status
Phase 4
Development phase
40 participants
Enrollment target

Study Summary

This will be a non-blinded feasibility (pilot) study comparing triple therapy nebulizer vs dry powdered inhalers (DPI) for care transitions in Chronic obstructive pulmonary disease (COPD) exacerbation patients. We hypothesize that patients treated in hospital and discharged on respiratory medications administered by nebulizers will exhibit better quality of life (QoL), symptom control, and lower COPD and all cause hospital readmission rates compared with patients treated with respiratory medications delivered by DPI. We aim to demonstrate that: 1. Patients treated and discharged on nebulized bronchodilators will have fewer readmissions to hospital at 30 and 90 days compared to the group utilizing DPI 2. The nebulizer group will demonstrate a longer duration of time until hospital readmission for COPD and all cause readmission compared to the group utilizing DPI 3. The nebulizer group will demonstrate better QoL (measured by the SGRQ - Saint George Respiratory Questionnaire) and symptom control (as measured by the CAT \& mMRC) compared to the group utilizing DPI.

Interventions

  • DEVICE Dry Powder Inhaler
  • DRUG Pulmicort
  • DEVICE Nebulizers
  • DRUG Brovana
  • DRUG Atrovent

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2017-10-03
Est. Completion 2020-04-01
Phase Phase 4

Sponsor

Wake Forest University Health Sciences

1,140 total trials

What the Registry Record Tells You About NCT03219866

The ClinicalTrials.gov registry entry for NCT03219866 describes a study currently listed as terminated, categorized as Phase 4. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Dry Powder Inhaler is the first listed.

NCT03219866 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03219866 about?

NCT03219866 is a clinical study titled "Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)". This will be a non-blinded feasibility (pilot) study comparing triple therapy nebulizer vs dry powdered inhalers (DPI) for care transitions in Chronic obstructive pulmonary disease (COPD) exacerbation patients. We hypothesize that patients treated in hospital and discharged on respiratory medicatio...

What is the current status of trial NCT03219866?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2017-10-03. Estimated completion is 2020-04-01.

What interventions are being tested in trial NCT03219866?

The interventions under investigation include: Dry Powder Inhaler (DEVICE), Pulmicort (DRUG), Nebulizers (DEVICE), Brovana (DRUG), Atrovent (DRUG).

Who is sponsoring clinical trial NCT03219866?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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