Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04612478 · ClinicalTrials.gov registry record · NA

Use of a Self-Directed Exercise Program (SDEP) Following Selected Lower Extremity Fractures

A NA study of Musculoskeletal Injury, sponsored by Wake Forest University Health Sciences.

Completed
Registry status
NA
Development phase
150
Enrollment target
2
Study locations

NCT04612478: Completed NA study of Musculoskeletal Injury, sponsored by Wake Forest University Health Sciences.

NCT04612478 is a NA study of Musculoskeletal Injury that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 150 participants, below the 512-participant average among 15 other Musculoskeletal Injury trials with a reported enrollment target (71% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04612478, a NA study of Musculoskeletal Injury, has completed, sponsored by Wake Forest University Health Sciences.

COMPLETED
Registry status
NA
Development phase
150 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to compare the effectiveness and value of clinic-based physical therapy (PT) and a home-based, self-directed exercise program (SDEP). The home exercise program will be developed by a team of physical therapists, orthopaedic trauma surgeons and experts in rehabilitation engagement in collaboration with patients recovering from traumatic lower-extremity injuries. The study will also determine which subgroups of individuals based on patient and injury characteristics are the best candidates for a home exercise program.

Primary Outcome

Measured through the rate of return to work/duty 12 months post discharge using the Work Productivity and Activity Impairment Questionnaire (WPAI)

Conditions Studied

Interventions

  • BEHAVIORAL Self-Directed Exercise Program
  • BEHAVIORAL Clinic-Based Physical

Study Locations (2)

North Carolina

  • Carolinas Medical Center - Charlotte

South Carolina

  • Greenville Health System - Greenville

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2018-03-14
Est. Completion 2023-11-02
Phase NA
Wake Forest University Health Sciences

1,140 total trials

What the finished NCT04612478 record still lists

NCT04612478 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 512-participant average among 15 other Musculoskeletal Injury trials with a reported enrollment target (71% lower).

The record links to 1 condition, with Musculoskeletal Injury appearing as the primary indexed condition, and to 2 interventions - of which Self-Directed Exercise Program is the first listed.

NCT04612478 reports a single indexed study location in North Carolina, South Carolina.

Frequently Asked Questions

What is clinical trial NCT04612478 about?

NCT04612478 is a clinical study titled "Use of a Self-Directed Exercise Program (SDEP) Following Selected Lower Extremity Fractures". The purpose of this study is to compare the effectiveness and value of clinic-based physical therapy (PT) and a home-based, self-directed exercise program (SDEP). The home exercise program will be developed by a team of physical therapists, orthopaedic trauma surgeons and experts in rehabilitation e...

What is the current status of trial NCT04612478?

This trial is currently completed. It is a NA study. The enrollment target is 150 participants. The study started on 2018-03-14. Estimated completion is 2023-11-02.

What conditions does trial NCT04612478 study?

This clinical trial studies the following conditions: Musculoskeletal Injury.

What interventions are being tested in trial NCT04612478?

The interventions under investigation include: Self-Directed Exercise Program (BEHAVIORAL), Clinic-Based Physical (BEHAVIORAL).

Who is sponsoring clinical trial NCT04612478?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04612478 being conducted?

This trial has 2 study locations across North Carolina, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Musculoskeletal Injury

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04612478's enrollment target sits among peer trials

150 6th of 15 higher than 10 of 15 other Musculoskeletal Injury trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Musculoskeletal Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00412594 · 150 participants · Phase 2

    Cladribine and Rituximab in Treating Patients With Hairy Cell Leukemia

  • NCT01484730 · 150 participants

    A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion

  • NCT01985919 · 150 participants

    Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples

  • NCT02016248 · 150 participants · NA

    SBRT Boost for Unfavorable Prostate Cancer'

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04612478, the US trial registry maintained by the National Library of Medicine. NCT04612478 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.