Wake Forest University Health Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Wake Forest University Health Sciences sits in the top decile of US sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count).

1,140 total trials 174 currently recruiting 724 completed early-phase tilt top decile by trial count

Wake Forest University Health Sciences: 1,140 sponsored US clinical trials, 174 recruiting.

Wake Forest University Health Sciences sponsors 1,140 registered US clinical trials on ClinicalTrials.gov, 174 of them currently recruiting, and 724 completed. 111 of these trials are in Phase 3-4 (later-stage) and 239 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 9 trials.

Top-decile sponsor footprint

Wake Forest University Health Sciences ranks in the top decile of sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

724 of 885 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,140 total, page 14 of 23

COMPLETED NA

Tranquil Moments II-CBT vs. Yoga for Worry

NCT02968238

COMPLETED Phase 2

Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma

NCT03056001

COMPLETED Phase 1

APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery

NCT03087591

COMPLETED NA

Internet-Delivered Positive Affect Program in Managing Emotion in Young Adult Cancer Survivors

NCT02832154

COMPLETED

Metabolic Changes in Blood Samples From Patients With Acute Myeloid Leukemia

NCT02581917

TERMINATED NA

Comparison of PVI Plus Catheter Ablation or PVI Alone for the Treatment of AFib for Patients With Paroxysmal Atrial Fibrillation

NCT03115554

COMPLETED NA

The New Executive and Appendix Template (NEAT) Study

NCT03419832

COMPLETED Phase 4

Loss of Resistance, w/wo Stimulation, For Epidural Placement

NCT03087604

TERMINATED Phase 2

Targeted Therapy in Treating Patients With Incurable Non-Small Cell Lung Cancer With Genetic Mutations

NCT02949843

COMPLETED NA

Parents as the Primary Sexuality Educators for Their Young Adults With Down Syndrome

NCT03135236

COMPLETED NA

The Urinary Incontinence Treatment Study

NCT03057834

COMPLETED

A Review of "Anesthesia Stat!" in the Pediatric Operating Room

NCT03152513

COMPLETED

Collection of Serum Samples in Studying Emotional Stress in Patients With Prostate Cancer

NCT03122743

COMPLETED Early Phase 1

Single Injection Adductor Canal Block Versus Continuous Adductor Canal Infusion for Total Knee Arthroplasty

NCT02991404

COMPLETED NA

Concussion Texting Study

NCT03099733

COMPLETED Phase 4

Evaluating Treatment Resistant Dermatitis TaroIIR

NCT03050294

COMPLETED Phase 2

IINB vs. QLB for Elective Open Inguinal Herniorrhaphy

NCT03007966

COMPLETED

Mobility Assessment Using Surrogates in Elderly Participants

NCT03032341

TERMINATED Phase 2

Efficacy of Intrathecal Oxytocin to Speed Recovery After Hip Surgery

NCT03011307

TERMINATED

Evaluating Dysphagia in Neonates With CHD

NCT03045757

COMPLETED NA

Ambient Lighting During Colonoscopy and Its Effect on Adenoma Detection Rate and Eye Fatigue

NCT04441242

TERMINATED Early Phase 1

Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer

NCT02827838

TERMINATED NA

Prospective Treatment Study of Catatonia Patients

NCT02734498

COMPLETED

Preparatory Work to Assess Adherence to Oral Chemotherapy

NCT02895542

COMPLETED Phase 1

Targeting Pro-Inflammatory Cells in Idiopathic Pulmonary Fibrosis: a Human Trial

NCT02874989

COMPLETED

EMPOWER-PULM (PULMonary Outcomes in Older Adults Empowered With Movement to Prevent Obesity and Weight Regain)

NCT03621098

COMPLETED NA

Empowered With Movement to Prevent Obesity and Weight Regain

NCT02923674

COMPLETED Phase 4

Comparison of Two Techniques of IV Lidocaine on Propofol Injection Pain

NCT03057704

COMPLETED

PARA-HEART Pilot Implementation

NCT02709135

COMPLETED Phase 2

Use of Vasopressin Following the Fontan Operation

NCT02975999

COMPLETED

Extubation in Pediatric Patients: An Observational Study

NCT02963532

COMPLETED NA

Role of Polyunsaturated Fatty Acids (PUFA)-Gene Interactions in Heath Disparities

NCT02962128

COMPLETED NA

Evaluation of Free Air Portable Air Powered Respirator

NCT02487147

COMPLETED NA

Valued EpiGenetic Glycemic ImprovEments Through Weight Loss

NCT02869659

COMPLETED Phase 1

Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02971397

COMPLETED

Symptom Burden and Unmet Supportive Care Needs in Lung Cancer Patients Undergoing First or Second Line Immunotherapy

NCT03741868

COMPLETED

Effectiveness of the Advocate Lutheran General Survivorship Center Programs

NCT02660996

COMPLETED NA

Biologics Anchoring Study

NCT03026153

TERMINATED Phase 2

LCI-GU-URO-CRI-001: Crizotinib in Patients With c-MET or RON-Positive Metastatic Urothelial Cancer

NCT02612194

COMPLETED

COcoa Supplement and Multivitamin Outcomes Study for the Mind

NCT03035201

COMPLETED Phase 1

The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients

NCT03139708

TERMINATED Phase 3

Leukemia Stem Cell Detection in Acute Myeloid Leukemia

NCT02927938

COMPLETED NA

The Impact of Art Therapy on the Relationships Between Individuals Diagnosed With Alzheimer's Disease and Their Care Partners

NCT06725251

COMPLETED NA

Mindfulness and Mechanisms of Pain Processing in Adults With Migraines

NCT02695498

COMPLETED

MRI and Cardio-Pulmonary Exercise Testing in Evaluating Exercise Intolerance in Patients With Stage I-III Breast Cancer After Chemotherapy Treatment

NCT02702830

COMPLETED NA

Pain Processing in Adults With Migraines

NCT02748577

TERMINATED

Pediatric Pain Assessment in the Emergency Department

NCT03157882

COMPLETED Phase 4

Genomic Outcomes of Metformin

NCT02986659

COMPLETED NA

The TREND Study: Tapered Reduction in Energy Intake as a Novel Approach to Dieting

NCT02837211

COMPLETED

Pulmonary Embolism Short-term Clinical Outcomes Registry

NCT02883491

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Phase Distribution

PhaseTrial count
Phase 1 96
Phase 2 143
Phase 3 31
Phase 4 80

What is open in the Wake Forest University Health Sciences pipeline

174 recruiting of 1,140 indexed (15% open); 724 completed (64%).

Phase mix: 111 late (III/IV) vs 239 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Wake Forest University Health Sciences: open-pipeline peers nationwide

Peers matched on 1,140 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share Wake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthUniversity of North Carolina, Chapel HillUniversity of FloridaBaylor UniversityCornell UniversityArrowhead Regional Medical CenterAurinia Pharmaceuticals
Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,140 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Wake Forest University Health Sciences page

1,140 registered trials is a research-attention snapshot, not an endorsement of Wake Forest University Health Sciences or any single study.

  • 174 of Wake Forest University Health Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Wake Forest University Health Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Wake Forest University Health Sciences pipeline card: 1,140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.