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NCT05871606 · ClinicalTrials.gov registry record · Phase 1
Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
A Phase 1 study of Cerebrovascular Disorders and Acute Cerebrovascular Disease, sponsored by Wake Forest University Health Sciences.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
- 2
- Study locations
NCT05871606: Recruiting Phase 1 study of Cerebrovascular Disorders and Acute Cerebrovascular Disease, sponsored by Wake Forest University Health Sciences.
NCT05871606 is a Phase 1 study of Cerebrovascular Disorders and Acute Cerebrovascular Disease that is actively recruiting participants, run by Wake Forest University Health Sciences. The registered enrollment target is 36 participants, below the 1,092-participant average among 8 other Cerebrovascular Disorders trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05871606, a Phase 1 study of Cerebrovascular Disorders and Acute Cerebrovascular Disease, is actively recruiting participants, sponsored by Wake Forest University Health Sciences.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this study is to determine the safety and feasibility of using inhaled nitric oxide (iNO) in patients undergoing intra-arterial mechanical thrombectomy (blood clot extraction or IAMT) for treatment of acute ischemic (non-bleeding) stroke (AIS).
Primary Outcome
To establish a maximum safe dose of iNO for acute ischemic (non-bleeding) stroke (AIS) patients, assessing for reperfusion hemorrhage/symptomatic intracranial hemorrhage (sICH)
Conditions Studied
Interventions
- DRUG iNO
Study Locations (2)
North Carolina
- Carolinas Medical Center - Charlotte
- Atrium Health - Charlotte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2025-11-11 |
| Est. Completion | 2028-12 |
| Phase | Phase 1 |
What NCT05871606 shows while recruiting
NCT05871606 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,092-participant average among 8 other Cerebrovascular Disorders trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Cerebrovascular Disorders appearing as the primary indexed condition, and to 1 intervention - of which iNO is the first listed.
NCT05871606 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT05871606 about?
NCT05871606 is a clinical study titled "Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy". The purpose of this study is to determine the safety and feasibility of using inhaled nitric oxide (iNO) in patients undergoing intra-arterial mechanical thrombectomy (blood clot extraction or IAMT) for treatment of acute ischemic (non-bleeding) stroke (AIS).
What is the current status of trial NCT05871606?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2025-11-11. Estimated completion is 2028-12.
What conditions does trial NCT05871606 study?
This clinical trial studies the following conditions: Cerebrovascular Disorders, Acute Cerebrovascular Disease.
What interventions are being tested in trial NCT05871606?
The interventions under investigation include: iNO (DRUG).
Who is sponsoring clinical trial NCT05871606?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05871606 being conducted?
This trial has 2 study locations across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cerebrovascular Disorders
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05871606's enrollment target sits among peer trials
36 7th of 8 higher than 2 of 8 other Cerebrovascular Disorders trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cerebrovascular Disorders trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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