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NCT07053774 · ClinicalTrials.gov registry record · Phase 2
Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain
A Phase 2 study of Pain, Acute, sponsored by Wake Forest University Health Sciences.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT07053774 is a Phase 2 study of Pain, Acute that is actively recruiting participants, run by Wake Forest University Health Sciences. The registered enrollment target is 24 participants, below the 101-participant average among 31 other Pain, Acute trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07053774, a Phase 2 study of Pain, Acute, is actively recruiting participants, sponsored by Wake Forest University Health Sciences.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this research study is to find out how well oxytocin works to reduce pain. Oxytocin will be given intravenously (IV) and as a nasal spray. The study team also hopes to find out if the participants age, weight, or sex effects how well the study drug works. Participants will be exposed to a heater on the skin at a training visit and rate how much pain different temperatures cause. On two separate visits, participants will use a nasal spray and get an IV infusion. After the IV and nasal spray, participants will rate the pain of the same skin heating temperature at various time points for 4 hours.
Conditions Studied
Interventions
- DRUG Intravenous oxytocin
- DRUG Intravenous placebo
- DRUG Intranasal oxytocin
- DRUG Intranasal placebo
Study Locations (1)
North Carolina
- Atrium Health Wake Forest Baptist - Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-11-05 |
| Est. Completion | 2026-06-28 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07053774
The ClinicalTrials.gov registry entry for NCT07053774 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 101-participant average among 31 other Pain, Acute trials with a reported enrollment target (76% lower). The listed sponsor is Wake Forest University Health Sciences, which has 1,140 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pain, Acute appearing as the primary indexed condition, and to 4 interventions - of which Intravenous oxytocin is the first listed.
NCT07053774 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT07053774 about?
NCT07053774 is a clinical study titled "Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain". The goal of this research study is to find out how well oxytocin works to reduce pain. Oxytocin will be given intravenously (IV) and as a nasal spray. The study team also hopes to find out if the participants age, weight, or sex effects how well the study drug works. Participants will be exposed to...
What is the current status of trial NCT07053774?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2025-11-05. Estimated completion is 2026-06-28.
What conditions does trial NCT07053774 study?
This clinical trial studies the following conditions: Pain, Acute.
What interventions are being tested in trial NCT07053774?
The interventions under investigation include: Intravenous oxytocin (DRUG), Intravenous placebo (DRUG), Intranasal oxytocin (DRUG), Intranasal placebo (DRUG).
Who is sponsoring clinical trial NCT07053774?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07053774 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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