University of Pennsylvania

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Pennsylvania sits in the top decile of US sponsors by registered trial count (#15 of 15,742 sponsors by registered trial count).

1,423 total trials 199 currently recruiting 982 completed early-phase tilt top decile by trial count

University of Pennsylvania: 1,423 sponsored US clinical trials, 199 recruiting.

University of Pennsylvania sponsors 1,423 registered US clinical trials on ClinicalTrials.gov, 199 of them currently recruiting, and 982 completed. 130 of these trials are in Phase 3-4 (later-stage) and 339 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of Pennsylvania ranks in the top decile of sponsors by registered trial count (#15 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 65/100

982 of 1,090 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,423 total, page 29 of 29

COMPLETED Phase 4

Relapse Prevention for Bipolar Type-II Disorder

NCT00044616

COMPLETED NA

Cognitive Behavioral Treatment of Pediatric Trichotillomania

NCT00043563

COMPLETED Phase 4

Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone)

NCT00006489

COMPLETED Phase 2

Tamoxifen-MRI Study

NCT00295100

COMPLETED

Ectopic Pregnancy Biomarkers

NCT00194168

COMPLETED Phase 4

Sertraline for Alcohol Dependence and Depression

NCT00004554

COMPLETED Phase 4

Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)

NCT00326781

COMPLETED

Risk Factors of Ectopic Pregnancy

NCT00194207

COMPLETED Phase 2

Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1

NCT00142844

COMPLETED Phase 2

Effectiveness of Amantadine and Propranolol for Treating Cocaine Dependence - 2

NCT00158132

COMPLETED Phase 4

Brain Imaging Study in Menopausal Women With and Without Major Depressive Disorder

NCT00626340

COMPLETED Phase 3

Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1

NCT00218660

COMPLETED Phase 4

The Role of GABA and Neurosteroids in Premenstrual Dysphoric Disorder

NCT00678574

COMPLETED Phase 3

Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence

NCT00167232

COMPLETED Phase 3

Treatment of Obsessive-Compulsive Disorder (OCD) in Children

NCT00000384

COMPLETED Phase 1

Piracetam for Treatment of Cocaine Addiction - 3

NCT00000198

COMPLETED Phase 2

Selegiline in Treatment of Cocaine Dependence - 2

NCT00000188

COMPLETED Phase 2

Ritanserin in Treatment of Cocaine Dependence - 1

NCT00000187

COMPLETED Phase 2

Carbamazepine Treatment for Cocaine Dependence - 5

NCT00000191

COMPLETED Phase 1

Cocaine in Parotid Saliva, Blood and Urine - 4

NCT00000190

COMPLETED Phase 2

Gepirone vs Placebo in Treatment of Cocaine Dependence - 3

NCT00000189

COMPLETED

High School Football and Adult Health

NCT03914573

COMPLETED Phase 2

Effectiveness and Costs of Enhanced Cocaine Treatments

NCT00167258

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Phase Distribution

PhaseTrial count
Phase 1 182
Phase 2 157
Phase 3 43
Phase 4 87

What is open in the University of Pennsylvania pipeline

199 recruiting of 1,423 indexed (14% open); 982 completed (69%).

Phase mix: 130 late (III/IV) vs 339 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Pennsylvania: open-pipeline peers nationwide

Peers matched on 1,423 registered trials and 14% open enrollment, not the therapeutic-area sidebar.

University of Pennsylvania sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 0%5%10%15%20% Total trials Recruiting share University of PennsylvaniaJohns Hopkins UniversityNovartis PharmaceuticalsYale UniversityGlaxoSmithKlineSeattle Institute for Biomedical and Clinical ResearchUniversity of Illinois at Urbana-ChampaignJohns Hopkins Bloomberg School of Public HealthMilton S. Hershey Medical Center
University of Pennsylvania sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Pennsylvania sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,423 trials (± recruiting share)

Sponsors near 14% open enrollment (± trial volume)

What to do with this University of Pennsylvania page

1,423 registered trials is a research-attention snapshot, not an endorsement of University of Pennsylvania or any single study.

  • 199 of University of Pennsylvania's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of Pennsylvania studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of Pennsylvania pipeline card: 1,423 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.