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NCT00326781 · ClinicalTrials.gov registry record · Phase 4
Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)
A Phase 4 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Phase 4
- Development phase
- 674
- Enrollment target
NCT00326781: Completed Phase 4 study, sponsored by University of Pennsylvania.
NCT00326781 is a Phase 4 study that has completed, run by University of Pennsylvania. The registered enrollment target is 674 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (30% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00326781, a Phase 4 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 674 participants
- Enrollment target
Study Summary
The purpose of this research study is to: 1. compare the effectiveness of a nicotine patch and nicotine nasal spray for smoking cessation; and 2. identify predictors of response to these alternate forms of nicotine replacement therapy (NRT).
Primary Outcome
A self-report measure of continuous abstinence at end of treatment. It is defined as the number of consecutive days without smoking a cigarette for each subject, as determined by the Timeline Followback (TLFB), completed by research staff. The TLFB is an assessment tool that obtains estimates of daily smoking. Using a calendar, people provide retrospective estimates of their daily smoking over a specified time period that can vary up to 12 months from the interview date. The TLFB has also been u
Interventions
- DRUG Nicotine Nasal Spray
- DRUG Nicoderm Transdermal Patch
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 674 participants |
| Start Date | 1999-12 |
| Est. Completion | 2004-08 |
| Phase | Phase 4 |
What the finished NCT00326781 record still lists
NCT00326781 is an interventional study that assigns participants to a tested intervention. The registered 674 participants enrollment target is mid-sized for trials with a published cap, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (30% higher).
The record links to 0 conditions, and to 2 interventions - of which Nicotine Nasal Spray is the first listed.
NCT00326781 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00326781 about?
NCT00326781 is a clinical study titled "Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)". The purpose of this research study is to: 1. compare the effectiveness of a nicotine patch and nicotine nasal spray for smoking cessation; and 2. identify predictors of response to these alternate forms of nicotine replacement therapy (NRT).
What is the current status of trial NCT00326781?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 674 participants. The study started on 1999-12. Estimated completion is 2004-08.
What interventions are being tested in trial NCT00326781?
The interventions under investigation include: Nicotine Nasal Spray (DRUG), Nicoderm Transdermal Patch (DRUG).
Who is sponsoring clinical trial NCT00326781?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00326781's enrollment target sits among peer trials
674 119th of 2000 higher than 1,882 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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