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NCT01374074 · ClinicalTrials.gov registry record
Racial Disparity in Barrett's Esophagus
A clinical trial of Barrett's Esophagus and Gastroesophageal Reflux Disease (GERD), sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- 255
- Enrollment target
- 1
- Study location
NCT01374074: Completed study of Barrett's Esophagus and Gastroesophageal Reflux Disease (GERD), sponsored by University of North Carolina, Chapel Hill.
NCT01374074 is a study of Barrett's Esophagus and Gastroesophageal Reflux Disease (GERD) that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 255 participants, below the 513-participant average among 22 other Barrett's Esophagus trials with a reported enrollment target (50% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01374074, a study of Barrett's Esophagus and Gastroesophageal Reflux Disease (GERD), has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- 255 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of the proposed research is to investigate the molecular mechanisms of racial disparity in Barrett's esophagus (BE), the premalignant lesion of esophageal adenocarcinoma. Specifically, the investigators hypothesize that environmental factors, genetic factors, and potentially gene environment interactions play crucial roles in the observed racial disparity in developing Barrett's esophagus. Patients are recruited through UNC hospitals prior to scheduled esophagogastroduodenoscopy (EGD). Participants complete a questionnaire, have body measurements obtained, and have blood, biopsies, and gastric aspirate collected. Participants also complete a 24 hour pH impedance test.
Primary Outcome
Odds ratios (ORs) and 95% confidence intervals (CI) will be used to estimate the association between gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) among Caucasian Americans and African Americans, separately, in relation to patterns of the exposures of interest (tobacco use, alcohol consumption, fruit and vegetable intake and other dietary measures, no NSAID use, and various measures of SES), with adjustments made for the frequency matching factors, age at reference (date of
Conditions Studied
Study Locations (1)
North Carolina
- University of North Carolina Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 255 participants |
| Start Date | 2011-03 |
| Est. Completion | 2014-01 |
What the finished NCT01374074 record still lists
NCT01374074 is an observational study that tracks outcomes without assigning an intervention. The registered 255 participants enrollment target is mid-sized for trials with a published cap, below the 513-participant average among 22 other Barrett's Esophagus trials with a reported enrollment target (50% lower).
The record links to 3 conditions, with Barrett's Esophagus appearing as the primary indexed condition, and to 0 interventions.
NCT01374074 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT01374074 about?
NCT01374074 is a clinical study titled "Racial Disparity in Barrett's Esophagus". The goal of the proposed research is to investigate the molecular mechanisms of racial disparity in Barrett's esophagus (BE), the premalignant lesion of esophageal adenocarcinoma. Specifically, the investigators hypothesize that environmental factors, genetic factors, and potentially gene environmen...
What is the current status of trial NCT01374074?
This trial is currently completed. The enrollment target is 255 participants. The study started on 2011-03. Estimated completion is 2014-01.
What conditions does trial NCT01374074 study?
This clinical trial studies the following conditions: Barrett's Esophagus, Gastroesophageal Reflux Disease (GERD), Intestinal Metaplasia.
Who is sponsoring clinical trial NCT01374074?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01374074 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Barrett's Esophagus
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01374074's enrollment target sits among peer trials
255 4th of 22 higher than 19 of 22 other Barrett's Esophagus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Barrett's Esophagus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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RECRUITING · NA
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