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NCT01625130 · ClinicalTrials.gov registry record · NA
Effect of Sulforaphane-rich Broccoli Sprout Homogenate on Ozone Induced Inflammation Through Modulation of NRF2
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT01625130 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 16 participants.
The verdict
NCT01625130, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
Purpose: To determine if modulation of NRF2 with a Sulforaphane enriched supplement modifies responses to O3. Participants: Recruitment of up to 70 healthy volunteers, ages 18-50, for completion of 36 volunteers. Procedures: This is a randomized, placebo controlled 2x2 crossover study of treatment with an NRF2 modifier versus placebo in healthy volunteers which will examine airway inflammation before and 4 hours after a 2 hour 0.4 ppm O3 exposure. Participants will be randomized to received either the NRF2 modifier, SFN oral supplement (i.e. broccoli sprout shake), or placebo (alfalfa shake) for 3 days followed by a 0.4 ppm O3 exposure for 2 hours. At least 2 weeks later subjects will return for a 2nd supplementation treatment (using the alternative supplement to that provided initially) followed by an ozone exposure identical to the initial one.
Interventions
- DIETARY_SUPPLEMENT Broccoli sprout homogenate
- DIETARY_SUPPLEMENT alfalfa sprout homogenate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2013-10 |
| Est. Completion | 2015-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01625130
The ClinicalTrials.gov registry entry for NCT01625130 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Broccoli sprout homogenate is the first listed.
NCT01625130 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01625130 about?
NCT01625130 is a clinical study titled "Effect of Sulforaphane-rich Broccoli Sprout Homogenate on Ozone Induced Inflammation Through Modulation of NRF2". Purpose: To determine if modulation of NRF2 with a Sulforaphane enriched supplement modifies responses to O3. Participants: Recruitment of up to 70 healthy volunteers, ages 18-50, for completion of 36 volunteers. Procedures: This is a randomized, placebo controlled 2x2 crossover study of treatment w...
What is the current status of trial NCT01625130?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2013-10. Estimated completion is 2015-06.
What interventions are being tested in trial NCT01625130?
The interventions under investigation include: Broccoli sprout homogenate (DIETARY_SUPPLEMENT), alfalfa sprout homogenate (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01625130?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
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