University of California, Irvine

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of California, Irvine sits in the top decile of US sponsors by registered trial count (#96 of 15,742 sponsors by registered trial count).

368 total trials 74 currently recruiting 228 completed early-phase tilt top decile by trial count

University of California, Irvine: 368 sponsored US clinical trials, 74 recruiting.

University of California, Irvine sponsors 368 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 228 completed. 27 of these trials are in Phase 3-4 (later-stage) and 92 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cancer, with 6 trials.

Top-decile sponsor footprint

University of California, Irvine ranks in the top decile of sponsors by registered trial count (#96 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

228 of 258 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

368 total, page 6 of 8

COMPLETED

Photo-Plethysmographic Camera to Monitor Heart Rate, Respiration Rate and Oxygen Saturation in Infants

NCT00989859

COMPLETED NA

Use of Hypothermia During Robotic Prostatectomy

NCT00915031

COMPLETED

Association Between Smoking, Brain Activity, Genes, and ADHD

NCT00915798

COMPLETED NA

Comparison of Motor and Sensory Response With Interstim Stimulation

NCT00943904

COMPLETED NA

Trial on the Effect of Optically Modified Fiber Mattress Covers on Sleep Disturbances in Patients With Chronic Back Pain

NCT00969540

COMPLETED NA

Addition of Pudendal Blocks to Pelvic Floor Physical Therapy for the Treatment of Pelvic Floor Tension Myalgia

NCT00928564

COMPLETED NA

Trial of Continuous Versus Cyclic Stimulation in Interstim Therapy

NCT00928499

TERMINATED Phase 4

Ischemic Conditioning (Delay Phenomenon) in Colorectal Surgery

NCT00887497

COMPLETED NA

Minimally Invasive Holmium:YAG Laser Blepharoplasty

NCT00842764

COMPLETED Phase 2

Robot-Assisted Hand Motor Therapy for Subjects With Hemiparetic Stroke

NCT01244243

COMPLETED Phase 1

A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.

NCT00830466

COMPLETED Phase 3

A D2 Receptor Occupancy and fMRI Study in Schizophrenic Subjects Treated With Lurasidone

NCT01979679

COMPLETED

The Investigation of a Fluorescence/Elastic Scattering Spectroscopy (F-ESS) Device for Oral Tissue Characterization

NCT00764569

COMPLETED

Chart Review of Those Who Have Had Open, Laparoscopic, Ureteroscopic, or Percutaneous Surgery

NCT00395564

COMPLETED Phase 1

A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.

NCT00800722

COMPLETED

Vascular Reactivity in Metabolic Syndrome and Diabetic Patients Using Diffuse Optical Spectroscopy

NCT00793481

COMPLETED

Incidence of Antibiotic Resistant E.Coli in Patients Undergoing Repeat Prostate Biopsy

NCT00915213

COMPLETED Phase 1

Optimizing Photodynamic Therapy of Cutaneous Neoplastic Diseases Via Structured Illumination and Real-time Dosimetry.

NCT00784108

COMPLETED NA

Tissue Donation for Myoblast Culture

NCT01119820

COMPLETED Phase 2

Trial of Aspirin and Arginine Restriction in Colorectal Cancer

NCT00578721

TERMINATED

Evaluation of the Accuracy and Precision of the Masimo Labs Pulse-Hemoglobin-Meter Monitor in Surgical Patients

NCT00762398

COMPLETED

Perceived Barriers to Exercise in Individuals Living With Spinal Cord Injury

NCT00786786

COMPLETED

Immunologic Abnormalities, Chronic Inflammation and Oxidative Stress in Chronic Kidney Disease

NCT00793806

COMPLETED NA

Cardiac CT's Role in Asymptomatic Patients With Diabetes and Metabolic Syndrome

NCT01564485

COMPLETED

A Pilot Study to Evaluate Optical Spectroscopy of Pigmented Skin Lesions

NCT00633516

TERMINATED NA

Study to Determine Effects of Vesicare on Return to Continence Post- Radical Prostatectomy

NCT00581061

COMPLETED NA

Femoral Arterial Access With Ultrasound Trial

NCT00667381

TERMINATED

Study to Determine if There Are Specific Clinical Factors to Determine Stent Encrustation

NCT00581178

COMPLETED

Lower Urinary Tract and Sexual Function in Women Following Surgery for Colorectal Disorders

NCT00667550

TERMINATED NA

Assessment and Determination of Chemotherapy Resistance in Newly-Diagnosed or First Relapse Leukemia Patients

NCT00631059

COMPLETED Phase 4

Adjunct Sedatives in Endoscopic Ultrasound (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) Procedures

NCT00937924

COMPLETED

PET-CT Scan Method to Monitor Pancreatic B-Cell Loss in Diabetes Mellitus

NCT00633763

COMPLETED Phase 2

Carboplatin+Nab-paclitaxel, Plus Trastuzumab (HER2+) or Bevacizumab (HER2-) in the Neoadjuvant Setting

NCT00618657

COMPLETED Phase 1

Safety Study of Nicotinamide to Treat Alzheimer's Disease

NCT00580931

COMPLETED

Combined Anticholinergic Medication and Sacral Neuromodulation to Treat Refractory Overactive Bladder

NCT01047046

COMPLETED

Characteristics Predictive of Pessary Success

NCT01123213

COMPLETED NA

3-D Endoanal Ultrasound: Normative Anatomy of the Anal Sphincter in Nulliparous Females

NCT01123109

COMPLETED Phase 1

Treatment of Vascular Lesions With a Tandem 532/1064 nm Laser

NCT00585338

TERMINATED

A Randomized Comparison Study of Aquacel Ag and Glucan II as Donor Site Dressings

NCT00581217

COMPLETED

Impact of Antenatal Betamethasone on Plasma Glucose Levels

NCT00585676

TERMINATED

A Prospective Study With a New Device for the Monitoring of Cerebral Oxygenation on Cardiac Surgery Patients

NCT00598936

COMPLETED Phase 1

A Prospective Study of a New Device for Monitoring Cerebral Oxygenation on Healthy Volunteers

NCT00598819

COMPLETED

Is the Cough Stress Test Equivalent to the 24 Hour Pad Test in the Assessment of Stress Incontinence?

NCT01123096

COMPLETED

Composite Graft Use in Abdominal Sacrocolpopexy Reduces Erosion Rates

NCT00581412

COMPLETED NA

Stress, Immunity and Cervical Cancer: Biobehavioral Outcomes

NCT00496106

COMPLETED

Carbohydrate Study, Chronic SCI

NCT00786435

COMPLETED

Inflammatory Bowel Disease Research Registry

NCT00574028

COMPLETED

Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)

NCT00610402

COMPLETED Phase 2

Trial of Dasatinib (Sprycel®) in Subjects With Hormone-refractory Prostate Cancer

NCT00570700

COMPLETED

Glucose Study, Spinal Cord Injury

NCT00786604

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Phase Distribution

PhaseTrial count
Phase 1 46
Phase 2 46
Phase 3 6
Phase 4 21

What is open in the University of California, Irvine pipeline

74 recruiting of 368 indexed (20% open); 228 completed (62%).

Phase mix: 27 late (III/IV) vs 92 early (I/II) (early-phase heavy).

Top condition: Cancer (6 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of California, Irvine: open-pipeline peers nationwide

Peers matched on 368 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%5%10%15%20%25% Total trials Recruiting share University of California, IrvineNorthwell HealthUNC Lineberger Comprehensive Cancer CenterRoswell Park Cancer InstituteNew York State Psychiatric InstituteUniversity of MiamiEndeavor HealthAcera SurgicalAlign Technology
University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 368 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of California, Irvine page

368 registered trials is a research-attention snapshot, not an endorsement of University of California, Irvine or any single study.

  • 74 of University of California, Irvine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Cancer is the condition University of California, Irvine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of California, Irvine pipeline card: 368 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.