UNC Lineberger Comprehensive Cancer Center

366 total trials 79 currently recruiting 209 completed

UNC Lineberger Comprehensive Cancer Center sponsors 366 registered US clinical trials on ClinicalTrials.gov, 79 of them currently recruiting, and 209 completed. 2 of these trials are in Phase 3-4 (later-stage) and 157 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 29 trials.

Trial Pipeline

366 total, page 5 of 8

COMPLETED NA

PET/MR in Assessing Response to Neoadjuvant Radiation Therapy in the Tx of High Grade Sarcomas

NCT03076333

COMPLETED Phase 2

Palbociclib and Cetuximab in Metastatic Colorectal Cancer

NCT03446157

COMPLETED Phase 2

PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC

NCT03442569

COMPLETED NA

Functional Sparing of Salivary Glands Using MRI Sialography for Patients Undergoing Definitive Radiation Therapy for Head and Neck Cancers of the Oropharynx

NCT03418792

COMPLETED

Pilot Evaluation of a Microfluidic Assay to Detect Minimal Residual Disease and Predict Relapse in AML Patients

NCT03488862

COMPLETED NA

Impact of Home-based Aerobic and Strength Exercises During Chemotherapy for Early Breast Cancer on Biomarkers of Aging

NCT03761706

COMPLETED NA

mHealth Physical Activity Intervention for Survivors of Adolescent and Young Adult Cancers

NCT03386383

COMPLETED

Assessing the Feasibility of Screening and Treating Anxiety and Depression in the Bone Marrow Transplant Population

NCT04025190

COMPLETED NA

Feasibility of an 8-week Tai Chi Chuan Intervention for Breast Cancer Survivors

NCT03196037

COMPLETED Phase 2

High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation

NCT03263442

COMPLETED NA

Enhancing Source Credibility in Tobacco Regulatory Communications

NCT03339206

COMPLETED NA

Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using A Couple-focused Web-based Tailored Symptom Self-management Program

NCT04350788

COMPLETED NA

A Culturally-adapted Colorectal Cancer Screening Decision Aid Designed for American Indians

NCT03569761

COMPLETED NA

A Patient Portal Tool, E-assist, for Supporting CRC Screening

NCT02798224

COMPLETED

Using PROMIS as Part of Routine Clinical Care for Racially Diverse Prostate and Bladder Cancer Patients

NCT03156244

COMPLETED Phase 2

Pembrolizumab TX-naive Distant Mets Melanoma and Use of (C11-AMT) PET at Baseline as Imaging Biomarker

NCT03089606

COMPLETED NA

Selective Image Guided Resection of Pathologically Documented Axillary Lymph Node Metastases

NCT03281720

COMPLETED NA

Home-based Exercise Intervention for Patients With Metastatic Prostate Cancer

NCT03672396

COMPLETED

Get REAL and HEEL Research Program

NCT03760536

TERMINATED Early Phase 1

18-FLT PET/MR Imaging to Predict Graft Failure and GVHD in Bone Marrow Transplant Patients

NCT03546556

COMPLETED Phase 2

P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC

NCT03077243

COMPLETED

Cancer Patients' Performance Status Assessed Using Cardiopulmonary Exercise Testing and Wearable Data Generation

NCT02844400

COMPLETED Phase 2

Study Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast Cancer

NCT02768701

TERMINATED Phase 1

A Phase I Study of Alisertib + R-EPOCH for Treatment of Myc-Positive Aggressive B-cell Lymphomas

NCT02700022

COMPLETED Phase 2

Phase II Trial of Sequential Consolidation With Pembrolizumab Followed by Nab-paclitaxel

NCT02684461

COMPLETED Phase 2

High Dose Cytarabine Followed by Pembrolizumab in Relapsed/Refractory AML

NCT02768792

COMPLETED Phase 2

Pembrolizumab + Radiation for Locally Adv SCC of the Head and Neck (SCCHN) Not Eligible Cisplatin

NCT02609503

COMPLETED Phase 2

Phase 2 Study of Pembrolizumab in Combination With Gemcitabine and Cisplatin as Neoadjuvant Therapy

NCT02690558

COMPLETED NA

Geriatric Assessment Reporting in Real Time (GARRT) in Non-electively Hospitalized Older Cancer Patients

NCT03951090

COMPLETED NA

Effect of Human Papillomavirus Self-Collection on Cervical Cancer Screening in High Risk Women: My Body, My Test 3

NCT02651883

COMPLETED

Culture of Circulating Tumor Cells Isolated From Cancer Patients With Metastatic Disease

NCT02781025

COMPLETED

Assessing Physical Fitness in Cancer Patients With Cardiopulmonary Exercise Testing and Wearable Data Generation

NCT02786628

TERMINATED Phase 2

Trial of Pregabalin for Granulocyte Colony-stimulating Factor (GCSF)-Induced Bone Pain

NCT03407430

COMPLETED Early Phase 1

A Pre-Op Window Study Evaluating Anti-Proliferative Effects of Atorvastatin on the Endometrium

NCT02767362

COMPLETED Phase 1

Dose-escalating AZD1775 + Concurrent Radiation + Cisplatin for Intermediate/High Risk HNSCC

NCT02585973

COMPLETED

Prospective Evaluation of Patient Reported Xerostomia After Whole Brain Radiation

NCT02682199

COMPLETED NA

Physical Activity to Maintain Quality of Life and Physical Function in Women With Metastatic Breast Cancer: a Pilot Study

NCT02682836

COMPLETED NA

Fitness in Allogeneic Stem Cell Transplantation

NCT02564458

COMPLETED NA

Pre-Post Study for Supporting Appropriate Implementation of Lung Cancer Screening

NCT03077230

TERMINATED Phase 2

Phase II Trial of Palbociclib in Patients With Metastatic Urothelial Cancer After Failure of First-Line Chemotherapy

NCT02334527

TERMINATED Phase 2

Cisplatin and Nab-paclitaxel for (N2) Defined NSCLC

NCT02276560

COMPLETED NA

Impact of Physical Activity on Biomarker of Aging and Body Composition Among Breast Cancer Survivors Age 65 and Older

NCT02328313

COMPLETED Phase 2

De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study

NCT02281955

COMPLETED NA

The Ability of Electronic Patient Symptom Reporting to Reduce Symptom Burden During Hospitalization for Chemotherapy

NCT02574897

COMPLETED Phase 2

Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN

NCT02124707

COMPLETED NA

The Effect of Walking on Fatigue After Chemotherapy in Patients 65 and Older

NCT02191982

COMPLETED NA

Comparison of the Sensitivity and Specificity of Acoustic Angiography to the Sensitivity and Specificity of Conventional Ultrasound

NCT02175628

COMPLETED NA

Physical Activity Intervention for Older Patients During Chemotherapy for Colorectal Cancer

NCT02191969

COMPLETED NA

The CARE Program: CAncer REhabilitation Pilot Study for Older Adults

NCT02306252

COMPLETED Phase 2

Genotype-Directed Study Of Irinotecan Dosing In FOLFIRI + BevacizumabTreated Metastatic Colorectal Cancer

NCT02138617

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Phase Distribution

PhaseTrial count
Phase 1 71
Phase 2 86
Phase 3 1
Phase 4 1

What the Pipeline for UNC Lineberger Comprehensive Cancer Center Shows

According to the ClinicalTrials.gov registry, UNC Lineberger Comprehensive Cancer Center is linked to 366 US clinical trials across every stage of research activity. Of those, 79 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 209 are already marked complete, representing roughly 57% of the total.

The phase mix for UNC Lineberger Comprehensive Cancer Center reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 157 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for UNC Lineberger Comprehensive Cancer Center is Breast Cancer with 29 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.