UNC Lineberger Comprehensive Cancer Center
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, UNC Lineberger Comprehensive Cancer Center sits in the top decile of US sponsors by registered trial count (#97 of 15,742 sponsors by registered trial count).
UNC Lineberger Comprehensive Cancer Center: 366 sponsored US clinical trials, 79 recruiting.
UNC Lineberger Comprehensive Cancer Center sponsors 366 registered US clinical trials on ClinicalTrials.gov, 79 of them currently recruiting, and 209 completed. 2 of these trials are in Phase 3-4 (later-stage) and 157 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 29 trials.
Top-decile sponsor footprint
UNC Lineberger Comprehensive Cancer Center ranks in the top decile of sponsors by registered trial count (#97 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
209 of 246 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (85.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
366 total, page 4 of 8
Financial Difficulty in Patients With Blood Cancer
NCT05212233
Geriatric-assessment Interventions to Address Functional Deficits in Older Adults w Multiple Myeloma
NCT04999085
Addressing Cancer-Related Financial Toxicity in Rural Oncology Care Settings
NCT04931251
Remote Monitoring of Lung Cancer Patient-Reported Outcomes Using Moovcare®
NCT05011890
Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study
NCT04978350
Impact of Vaping Prevention Advertisements
NCT04836455
Transitioning Care: Perspectives of Older Women With Early Breast Cancer on Current Telemedicine Modalities
NCT04990934
Correcting Public Misperceptions About Very Low Nicotine Content Cigarettes
NCT04974489
Mobile Coaching to Improve HPV Vaccine Delivery
NCT05105711
Development and Application of a Novel Digital Array PCR for Acute Myeloid Leukemia (AML)
NCT04920188
Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT)
NCT04645667
Chemotherapy-related Cognitive Impairment and Acute Leukemia
NCT04644419
Feasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)
NCT04492007
Contrast-Enhanced Ultrasound for Kidney Cancer Subtyping and Staging
NCT04021238
An Evaluation of the Families Addressing Cancer Together (FACT) Intervention
NCT04342871
PET/MR Characterization of Renal Cell Carcinomas
NCT04271254
RN-Led Palliative and Supportive Care Intervention
NCT04570709
Clinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis
NCT04076696
Olanzapine for Nausea/Vomiting Prophylaxis in Recipients of Hematopoietic Stem Cell Transplants
NCT04535141
Effect of Incidental Findings Information on Lung Cancer Screening Intent
NCT04432753
PSMA-PET/MRI Unfavorable-Risk Target Volume Pilot Study
NCT04176497
Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
NCT04406714
Patient-centered Communication About Healthy Weight in Early Breast Cancer
NCT04504201
The HealthScore Health Coaching Program
NCT04923997
Improving Quality of Life After Thoracic Surgery Using Patient-Reported Outcomes
NCT04342260
LCCC1931:Post-treatment Intervention in Women With Breast Cancer (70y/o+)
NCT04292847
Application of Plasma Circulating HPV DNA Testing to Management of Cervical Intraepithelial Neoplasia
NCT04274465
Early Intervention for Impairments Identified During Comprehensive Geriatric Assessment in Patients With Bladder Cancer
NCT04273724
Fathers and Mothers Invested in Lives of Their Youth (FAMILY) Study: A Pilot Intervention
NCT04092816
Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer
NCT04033419
Contrast-enhanced Ultrasound as a Screening Tool for Kidney Cancer in Patients With Von-Hippel Lindau
NCT03907657
High Intensity Interval Training in Endometrial Cancer
NCT04025229
Precision Dosing of Tyrosine Kinase Inhibitors in CML Patients
NCT03885830
The STEPP Study: Sensors To Evaluate Physical Performance
NCT03952767
Window of Opportunity Pilot Study of Pembrolizumab in Obesity-driven Endometrial Cancer
NCT03694834
Academic-Industrial Partnership for Translation of Acoustic Angiography
NCT03544268
Testing the Utilization of a Mobile Health App for Patients Undergoing Cystectomy Surgery for Bladder Cancer
NCT03862105
An Exploratory Study of Pembrolizumab Plus Entinostat in Non-Inflamed Stage III/IV Melanoma
NCT03765229
A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion
NCT03597009
Novel MRI Sequence MR Fingerprinting in Breast MRI Feasibility Study
NCT03846947
PET/MR in Surgical Planning for Breast CA Treated With Neoadj Chemo
NCT04149353
Window of Opportunity Trial of Entinostat in Patients With Newly Diagnosed Stage I-IIIC,TNBC
NCT03361800
GRADE-SRM: Genomic Risk Assessment and Decisional Evaluation for Small Renal Masses
NCT03819569
Multimedia Aid Gynecologic Counseling and Consent
NCT03899441
MOtiVating Endometrial Cancer Survivors With Activity Monitors and Tailored Feedback
NCT03820024
Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma
NCT03620019
Promoting Physical Activity in Young Adult Cancer Survivors Using mHealth and Adaptive Tailored Feedback Strategies
NCT03569605
Efficacy of a Couple-Focused mHealth Symptom Self-management Program
NCT03489057
ARFI, VisR and DDAI Ultrasound for Improving Discrimination of Malignant and Unresponsive Breast Cancer
NCT03785782
Trial of Parotid Sparing Whole Brain Radiation
NCT03595878
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 71 |
| Phase 2 | 86 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Therapeutic Areas
What is open in the UNC Lineberger Comprehensive Cancer Center pipeline
79 recruiting of 366 indexed (22% open); 209 completed (57%).
Phase mix: 2 late (III/IV) vs 157 early (I/II) (early-phase heavy).
Top condition: Breast Cancer (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
UNC Lineberger Comprehensive Cancer Center: open-pipeline peers nationwide
Peers matched on 366 registered trials and 22% open enrollment, not the therapeutic-area sidebar.
UNC Lineberger Comprehensive Cancer Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 366 trials (± recruiting share)
- Roswell Park Cancer Institute · 365 trials · 16% recruiting
- University of California, Irvine · 368 trials · 20% recruiting
- New York State Psychiatric Institute · 364 trials · 3% recruiting
- Northwell Health · 370 trials · 22% recruiting
Sponsors near 22% open enrollment (± trial volume)
- Women and Infants Hospital of Rhode Island · 22% recruiting · 65 trials
- Merck Sharp & Dohme · 22% recruiting · 558 trials
- Henry M. Jackson Foundation for the Advancement of Military Medicine · 22% recruiting · 60 trials
- AbbVie · 21% recruiting · 526 trials
Related
What to do with this UNC Lineberger Comprehensive Cancer Center page
366 registered trials is a research-attention snapshot, not an endorsement of UNC Lineberger Comprehensive Cancer Center or any single study.
- 79 of UNC Lineberger Comprehensive Cancer Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Breast Cancer is the condition UNC Lineberger Comprehensive Cancer Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
UNC Lineberger Comprehensive Cancer Center pipeline card: 366 registered trials from official public datasets.Report a data error.