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NCT02768701 · ClinicalTrials.gov registry record · Phase 2

Study Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast Cancer

A Phase 2 study of Triple Negative Breast Cancer, sponsored by UNC Lineberger Comprehensive Cancer Center.

Completed
Registry status
Phase 2
Development phase
40
Enrollment target
5
Study locations

NCT02768701 is a Phase 2 study of Triple Negative Breast Cancer that has completed, run by UNC Lineberger Comprehensive Cancer Center. The registered enrollment target is 40 participants, below the 246-participant average among 118 other Triple Negative Breast Cancer trials with a reported enrollment target (84% lower). The trial reports 5 study locations across 3 states.

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The verdict

NCT02768701, a Phase 2 study of Triple Negative Breast Cancer, has completed, sponsored by UNC Lineberger Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
40 participants
Enrollment target
5
Study locations

Study Summary

The purpose of this study is to evaluate pembrolizumab therapy in patients with triple-negative breast cancer (TNBC) who have received at least one prior line of therapy.

Interventions

  • DRUG Pembrolizumab
  • DRUG Cyclophosphamide

Study Locations (5)

North Carolina

  • Lineberger Comprehensive Cancer Center - Chapel Hill
  • Cone Health Cancer Center - Greensboro
  • Rex Cancer Center - Raleigh

District of Columbia

  • George Washington University-Medical Faculty Associates - Washington D.C.

Pennsylvania

  • University of Pittsburgh Medical Center - Pittsburgh

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2016-10-18
Est. Completion 2023-05-01
Phase Phase 2

What the Registry Record Tells You About NCT02768701

The ClinicalTrials.gov registry entry for NCT02768701 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 246-participant average among 118 other Triple Negative Breast Cancer trials with a reported enrollment target (84% lower). The listed sponsor is UNC Lineberger Comprehensive Cancer Center, which has 366 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Triple Negative Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT02768701 reports 5 study locations spanning 3 distinct geographic areas - top geographies include North Carolina, District of Columbia, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT02768701 about?

NCT02768701 is a clinical study titled "Study Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast Cancer". The purpose of this study is to evaluate pembrolizumab therapy in patients with triple-negative breast cancer (TNBC) who have received at least one prior line of therapy.

What is the current status of trial NCT02768701?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2016-10-18. Estimated completion is 2023-05-01.

What conditions does trial NCT02768701 study?

This clinical trial studies the following conditions: Triple Negative Breast Cancer.

What interventions are being tested in trial NCT02768701?

The interventions under investigation include: Pembrolizumab (DRUG), Cyclophosphamide (DRUG).

Who is sponsoring clinical trial NCT02768701?

This trial is sponsored by UNC Lineberger Comprehensive Cancer Center, which has 366 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02768701 being conducted?

This trial has 5 study locations across District of Columbia, North Carolina, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.