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NCT00750698 · ClinicalTrials.gov registry record · Phase 2

A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on Erlotinib

A Phase 2 study, sponsored by Syndax Pharmaceuticals.

Terminated
Registry status
Phase 2
Development phase
8
Enrollment target

NCT00750698: Clinical Trial Phase 2 study, sponsored by Syndax Pharmaceuticals.

NCT00750698 is a Phase 2 study that was terminated before completion, run by Syndax Pharmaceuticals. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00750698, a Phase 2 study, was terminated before completion, sponsored by Syndax Pharmaceuticals.

TERMINATED
Registry status
Phase 2
Development phase
8 participants
Enrollment target

Study Summary

To evaluate the tumor responses to SNDX-275 (entinostat) in combination with continued erlotinib in participants with non-small Cell Lung Carcinoma (NSCLC) who are progressing on erlotinib.

Interventions

  • DRUG Entinostat
  • DRUG Erlotinib

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2008-08
Est. Completion 2010-06
Phase Phase 2
Syndax Pharmaceuticals

25 total trials

Why NCT00750698 stopped before completion

NCT00750698 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).

The record links to 0 conditions, and to 2 interventions - of which Entinostat is the first listed.

NCT00750698 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00750698 about?

NCT00750698 is a clinical study titled "A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on Erlotinib". To evaluate the tumor responses to SNDX-275 (entinostat) in combination with continued erlotinib in participants with non-small Cell Lung Carcinoma (NSCLC) who are progressing on erlotinib.

What is the current status of trial NCT00750698?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2008-08. Estimated completion is 2010-06.

What interventions are being tested in trial NCT00750698?

The interventions under investigation include: Entinostat (DRUG), Erlotinib (DRUG).

Who is sponsoring clinical trial NCT00750698?

This trial is sponsored by Syndax Pharmaceuticals, which has 25 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00750698's enrollment target sits among peer trials

8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00750698, the US trial registry maintained by the National Library of Medicine. NCT00750698 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.