Regeneron Pharmaceuticals

280 total trials 61 currently recruiting 151 completed

Regeneron Pharmaceuticals sponsors 280 registered US clinical trials on ClinicalTrials.gov, 61 of them currently recruiting, and 151 completed. 83 of these trials are in Phase 3-4 (later-stage) and 174 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Dermatitis, Atopic, with 6 trials.

Trial Pipeline

280 total, page 5 of 6

COMPLETED Phase 1

Study of Fasinumab (REGN475) in Healthy Japanese and Caucasian Subjects

NCT02516618

COMPLETED Phase 2

Study of Dupilumab in Adult Participants With Active Eosinophilic Esophagitis (EoE)

NCT02379052

TERMINATED Phase 2

Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-Related Macular Degeneration (AMD)

NCT02418754

COMPLETED Phase 2

Study of REGN475 in Patients With Pain Due to Osteoarthritis of the Knee or Hip

NCT02447276

COMPLETED Phase 3

Study of Alirocumab (REGN727/SAR236553) in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) Undergoing Low-density Lipoprotein (LDL) Apheresis Therapy

NCT02326220

COMPLETED Phase 2

Study of REGN1500 in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

NCT02265952

COMPLETED Phase 1

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

NCT02383212

COMPLETED Phase 1

Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies

NCT02290951

COMPLETED Phase 3

Study of Dupilumab (REGN668/SAR231893) Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

NCT02277769

COMPLETED Phase 1

Study of Intravitreal (IVT) REGN910-3 and IVT REGN910 in Patients With Either Neovascular ("Wet") Age Related Macular Degeneration (AMD) or Diabetic Macular Edema (DME)

NCT01997164

COMPLETED Phase 3

Study of Dupilumab Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

NCT02277743

TERMINATED Phase 1

Study of REGN1193 in Patients With Type 2 Diabetes Mellitus

NCT02284425

COMPLETED Phase 3

Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic Dermatitis

NCT02260986

COMPLETED Phase 2

Study of Dupilumab and Immune Responses in Adults With Atopic Dermatitis (AD)

NCT02210780

COMPLETED Phase 1

Study of the Safety and Tolerability of REGN2222(SAR438584) in Healthy Adult Volunteers

NCT02121080

COMPLETED Phase 1

Study to Assess the Safety and Tolerability of Multiple Ascending Doses of REGN1500

NCT02107872

COMPLETED Phase 1

Single-dose Study to Describe the Pharmacodynamics (PD) and Safety of Sarilumab (REGN88/SAR153191) and Tocilizumab in Adults With Rheumatoid Arthritis (RA)

NCT02097524

COMPLETED Phase 1

Phase 1 Safety Study With Intravitreal (IVT) REGN2176-3 in Patients Aged 50 Years and Older With Wet AMD

NCT02061865

COMPLETED Phase 2

Study to Determine the Safety and Effectiveness of Dupilumab for Treatment of Atopic Dermatitis (AD)

NCT01979016

COMPLETED Phase 2

Study of the Safety and Efficacy of REGN1033 (SAR391786) in Patients With Sarcopenia

NCT01963598

COMPLETED Phase 3

Open-label Study of Dupilumab in Patients With Atopic Dermatitis

NCT01949311

COMPLETED Phase 3

Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab (REGN727/ SAR236553) in Patients With Primary Hypercholesterolemia (ODYSSEY CHOICE 1)

NCT01926782

COMPLETED Phase 1

Single Ascending-dose Study of the Safety, Tolerability, and Pharmacokinetics of REGN1908-1909 in Allergic, Adult Subjects

NCT01922661

COMPLETED Phase 1

Study to Assess the Safety and Bioeffect of REGN1033 (SAR391786)

NCT01910220

COMPLETED Phase 1

An Ascending Single-Dose Study of the Safety, Tolerability and Bioeffect of REGN1193

NCT01933763

COMPLETED Phase 1

Study to Assess the Safety and Tolerability of Ascending Single Doses of REGN2009 in Healthy Volunteers

NCT01893528

COMPLETED Phase 2

Study of Dupilumab Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

NCT01859988

COMPLETED Phase 1

Study to Assess the Safety and Tolerability of Single Doses of REGN1500

NCT01749878

COMPLETED Phase 3

Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)

NCT01730053

COMPLETED Phase 4

Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection)

NCT01722045

COMPLETED Phase 1

Study of REGN1400 Alone and in Combination With Erlotinib or Cetuximab in Patients With Certain Types of Cancer

NCT01727869

COMPLETED Phase 3

Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)

NCT01730040

COMPLETED Phase 1

Nesvacumab (REGN910/ SAR307746) and Aflibercept ("Ziv-aflibercept" in the U.S.) in Patients With Advanced Solid Malignancies

NCT01688960

COMPLETED Phase 1

Study to Assess the Safety and Tolerability of Multiple Ascending Doses of REGN1033 (SAR391786)

NCT01720576

COMPLETED Phase 3

Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE)

NCT01709513

COMPLETED Phase 3

Study to Assess the Clinical Efficacy and Safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) in Patients With Branch Retinal Vein Occlusion (BRVO)

NCT01521559

COMPLETED Phase 2

Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

NCT01576484

COMPLETED Phase 2

A Study of Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Gene

NCT01604824

COMPLETED Phase 1

A Study to Assess the Safety and Tolerability of Single Ascending Doses of REGN1033(SAR391786)

NCT01507402

COMPLETED Phase 1

Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of REGN668 Administered Subcutaneously to Healthy Volunteers

NCT01484600

TERMINATED Phase 3

Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flares

NCT01459796

COMPLETED Phase 4

Efficacy and Safety of Colchicine for the Prevention of Gout Flares During the Initiation of Allopurinol

NCT01451645

COMPLETED Phase 3

Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Patients With Diabetic Macular Edema

NCT01363440

COMPLETED Phase 2

Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemia

NCT01266876

COMPLETED Phase 1

Study of Nesvacumab (REGN910/ SAR307746)

NCT01271972

COMPLETED Phase 1

Sequential Ascending Dose Study to Assess the Safety and Tolerability of REGN668 (SAR231893) in Patients With Atopic Dermatitis

NCT01259323

COMPLETED Phase 1

Ascending Dose Study of the Safety and Tolerability of REGN728 in Healthy Volunteers

NCT01197391

COMPLETED

A Study of Tocilizumab in Patients With Rheumatoid Arthritis

NCT01187563

COMPLETED Phase 1

Ascending Multi-dose Study of REGN727(SAR236553) With and Without Concomitant Atorvastatin

NCT01161082

COMPLETED Phase 1

Ascending Dose Study of the Safety and Tolerability of REGN727 (SAR236553) in Healthy Volunteers

NCT01074372

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What the Pipeline for Regeneron Pharmaceuticals Shows

According to the ClinicalTrials.gov registry, Regeneron Pharmaceuticals is linked to 280 US clinical trials across every stage of research activity. Of those, 61 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 151 are already marked complete, representing roughly 54% of the total.

The phase mix for Regeneron Pharmaceuticals reports 83 late-stage studies (Phase 3 and Phase 4 combined) and 174 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Regeneron Pharmaceuticals is Dermatitis, Atopic with 6 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.