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NCT01197391 · ClinicalTrials.gov registry record · Phase 1

Ascending Dose Study of the Safety and Tolerability of REGN728 in Healthy Volunteers

A Phase 1 study, sponsored by Regeneron Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
48
Enrollment target

NCT01197391 is a Phase 1 study that has completed, run by Regeneron Pharmaceuticals. The registered enrollment target is 48 participants.

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The verdict

NCT01197391, a Phase 1 study, has completed, sponsored by Regeneron Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
48 participants
Enrollment target

Study Summary

This study will test the safety and tolerability (how the body reacts to the drug) of REGN728 compared with placebo (an inactive substance that contains no medicine) in healthy subjects. The study drug and placebo will be administered by subcutaneous injection (under the skin) at the clinic visit. There will be 14 clinic visits, which will include 4 overnight stays. Subjects will be monitored by the study staff for side effects and the body's response to the study drug. Vital signs (blood pressure, temperature, breathing and heart rate) will be checked, blood and urine samples will be collected at some or all visits.

Interventions

  • BIOLOGICAL REGN728

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2010-08
Est. Completion 2012-03
Phase Phase 1

Sponsor

Regeneron Pharmaceuticals

280 total trials

What the Registry Record Tells You About NCT01197391

The ClinicalTrials.gov registry entry for NCT01197391 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Regeneron Pharmaceuticals, which has 280 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which REGN728 is the first listed.

NCT01197391 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01197391 about?

NCT01197391 is a clinical study titled "Ascending Dose Study of the Safety and Tolerability of REGN728 in Healthy Volunteers". This study will test the safety and tolerability (how the body reacts to the drug) of REGN728 compared with placebo (an inactive substance that contains no medicine) in healthy subjects. The study drug and placebo will be administered by subcutaneous injection (under the skin) at the clinic visit. T...

What is the current status of trial NCT01197391?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2010-08. Estimated completion is 2012-03.

What interventions are being tested in trial NCT01197391?

The interventions under investigation include: REGN728 (BIOLOGICAL).

Who is sponsoring clinical trial NCT01197391?

This trial is sponsored by Regeneron Pharmaceuticals, which has 280 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.