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NCT01963598 · ClinicalTrials.gov registry record · Phase 2

Study of the Safety and Efficacy of REGN1033 (SAR391786) in Patients With Sarcopenia

A Phase 2 study, sponsored by Regeneron Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
253
Enrollment target

NCT01963598: Completed Phase 2 study, sponsored by Regeneron Pharmaceuticals.

NCT01963598 is a Phase 2 study that has completed, run by Regeneron Pharmaceuticals. The registered enrollment target is 253 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01963598, a Phase 2 study, has completed, sponsored by Regeneron Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
253 participants
Enrollment target

Study Summary

This is a randomized, double-blind, placebo-controlled, multicenter phase 2 study of the safety and efficacy of 3-month subcutaneous (SC) REGN1033 (SAR391786) treatment in patients with sarcopenia.

Primary Outcome

The primary endpoint in the study is the percent change in total lean body mass measured by DEXA (dual energy X-ray absorptiometry) from baseline (day 1) to week 12 (day 85).

Interventions

  • DRUG placebo
  • DRUG REGN1033 (SAR391786)

Trial Details

FieldValue
Enrollment Target 253 participants
Start Date 2013-11
Est. Completion 2015-02
Phase Phase 2
Regeneron Pharmaceuticals

280 total trials

What the finished NCT01963598 record still lists

NCT01963598 is an interventional study that assigns participants to a tested intervention. The registered 253 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% higher).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT01963598 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01963598 about?

NCT01963598 is a clinical study titled "Study of the Safety and Efficacy of REGN1033 (SAR391786) in Patients With Sarcopenia". This is a randomized, double-blind, placebo-controlled, multicenter phase 2 study of the safety and efficacy of 3-month subcutaneous (SC) REGN1033 (SAR391786) treatment in patients with sarcopenia.

What is the current status of trial NCT01963598?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 253 participants. The study started on 2013-11. Estimated completion is 2015-02.

What interventions are being tested in trial NCT01963598?

The interventions under investigation include: placebo (DRUG), REGN1033 (SAR391786) (DRUG).

Who is sponsoring clinical trial NCT01963598?

This trial is sponsored by Regeneron Pharmaceuticals, which has 280 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01963598's enrollment target sits among peer trials

253 220th of 2000 higher than 1,781 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01963598, the US trial registry maintained by the National Library of Medicine. NCT01963598 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.