Dompé Farmaceutici S.p.A

27 total trials 4 currently recruiting 18 completed

Dompé Farmaceutici S.p.A sponsors 27 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 18 completed. 9 of these trials are in Phase 3-4 (later-stage) and 16 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Dry Eye Disease, with 2 trials.

Trial Pipeline

27 total, page 1 of 1

RECRUITING Phase 3

Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

NCT07453888

RECRUITING Phase 3

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

NCT07519902

RECRUITING Phase 2

An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease

NCT07503886

RECRUITING Phase 3

An Efficacy and Safety Study of DFL24498 in the Treatment of AKC

NCT07395232

TERMINATED

Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry Eye

NCT06411132

COMPLETED Phase 2

A Safety and Efficacy Study of 2 Dosing Regimens of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution Compared With Vehicle in Patients With Dry Eye Disease.

NCT06244316

COMPLETED

DEFENDO Long Term Follow-up Study in Stage 1 NK Patients

NCT05552261

COMPLETED Phase 2

Add-on Reparixin in Adult Patients With ARDS

NCT05496868

TERMINATED Phase 3

Reparixin add-on Therapy to Standard Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia

NCT05254990

COMPLETED Phase 3

Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease

NCT05136170

COMPLETED Phase 3

Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study)

NCT05133180

COMPLETED Phase 3

Study on Efficacy and Safety of Reparixin in the Treatment of Hospitalized Patients With Severe COVID-19 Pneumonia.

NCT04878055

TERMINATED Phase 2

A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function

NCT04628481

TERMINATED Phase 2

A Study to Assess Efficacy/Safety of Ladarixin in Type 1 Diabetes Patients With Preserved ß-cell Function at Baseline.

NCT04899271

COMPLETED Phase 4

Study to Evaluate OXERVATE® in Patients With Stage 1 Neurotrophic Keratitis

NCT04485546

COMPLETED Phase 2

A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye

NCT03982368

COMPLETED Phase 1

Study to Evaluate Safety, Tolerability & PK of rhNGF in Healthy Volunteers

NCT03836859

COMPLETED Phase 2

An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry Eye

NCT03019627

COMPLETED Phase 1

Study to Evaluate Safety and Efficacy of rhNGF Eye Drops Solution Versus Vehicle in Patients With Glaucoma

NCT02855450

COMPLETED Phase 2

A Double-blind Study of Paclitaxel in Combination With Reparixin or Placebo for Metastatic Triple-Negative Breast Cancer

NCT02370238

COMPLETED Phase 2

Evaluation of Efficacy of 20 µg/ml rhNGF New Formulation (With Anti-oxidant) in Patients With Stage 2 and 3 NK

NCT02227147

COMPLETED Phase 2

Efficacy and Safety of Reparixin in Pancreatic Islet Auto-transplantation

NCT01967888

TERMINATED Phase 2

Pilot Study to Evaluate Safety & Biological Effects of Orally Administered Reparixin in Early Breast Cancer

NCT01861054

COMPLETED Phase 3

Study to Assess Efficacy & Safety of Reparixin in Pancreatic Islet Transplantation

NCT01817959

COMPLETED Phase 1

Pilot Study to Evaluate Reparixin With Weekly Paclitaxel in Patients With HER 2 Negative Metastatic Breast Cancer (MBC)

NCT02001974

COMPLETED Phase 2

Reparixin in Prevention of Delayed Graft Function After Kidney Transplantation

NCT00248040

COMPLETED Phase 2

Repertaxin in Prevention of Primary Graft Dysfunction After Lung Transplantation

NCT00224406

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 13
Phase 3 8
Phase 4 1

What the Pipeline for Dompé Farmaceutici S.p.A Shows

According to the ClinicalTrials.gov registry, Dompé Farmaceutici S.p.A is linked to 27 US clinical trials across every stage of research activity. Of those, 4 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 18 are already marked complete, representing roughly 67% of the total.

The phase mix for Dompé Farmaceutici S.p.A reports 9 late-stage studies (Phase 3 and Phase 4 combined) and 16 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Dompé Farmaceutici S.p.A is Dry Eye Disease with 2 linked trials, and 5 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.