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NCT00357253 · ClinicalTrials.gov registry record · Phase 1

Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma

A Phase 1 study, sponsored by Pediatric Brain Tumor Consortium.

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT00357253 is a Phase 1 study that has completed, run by Pediatric Brain Tumor Consortium. The registered enrollment target is 24 participants.

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The verdict

NCT00357253, a Phase 1 study, has completed, sponsored by Pediatric Brain Tumor Consortium.

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Capecitabine may make tumor cells more sensitive to radiation therapy. Giving capecitabine together with radiation therapy may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of capecitabine when given together with radiation therapy in treating young patients with newly diagnosed, nonmetastatic brain stem glioma or high-grade glioma.

Interventions

  • DRUG capecitabine
  • RADIATION radiation therapy

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2006-01
Est. Completion 2010-03
Phase Phase 1

Sponsor

Pediatric Brain Tumor Consortium

27 total trials

What the Registry Record Tells You About NCT00357253

The ClinicalTrials.gov registry entry for NCT00357253 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pediatric Brain Tumor Consortium, which has 27 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which capecitabine is the first listed.

NCT00357253 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00357253 about?

NCT00357253 is a clinical study titled "Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma". RATIONALE: Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Capecitabine may make tumor cells more sensitive to rad...

What is the current status of trial NCT00357253?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2006-01. Estimated completion is 2010-03.

What interventions are being tested in trial NCT00357253?

The interventions under investigation include: capecitabine (DRUG), radiation therapy (RADIATION).

Who is sponsoring clinical trial NCT00357253?

This trial is sponsored by Pediatric Brain Tumor Consortium, which has 27 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.