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NCT03904862 · ClinicalTrials.gov registry record · Phase 1

Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery

A Phase 1 study, sponsored by Pediatric Brain Tumor Consortium.

Terminated
Registry status
Phase 1
Development phase
21
Enrollment target

NCT03904862 is a Phase 1 study that was terminated before completion, run by Pediatric Brain Tumor Consortium. The registered enrollment target is 21 participants.

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The verdict

NCT03904862, a Phase 1 study, was terminated before completion, sponsored by Pediatric Brain Tumor Consortium.

TERMINATED
Registry status
Phase 1
Development phase
21 participants
Enrollment target

Study Summary

This is a multi center, Phase I, Phase II and surgical study of the CX-4945 drug (silmitasertib sodium) for patients with recurrent SHH (Sonic Hedgehog) medulloblastoma

Interventions

  • DRUG CX 4945

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2019-07-25
Est. Completion 2025-08-11
Phase Phase 1

Sponsor

Pediatric Brain Tumor Consortium

27 total trials

What the Registry Record Tells You About NCT03904862

The ClinicalTrials.gov registry entry for NCT03904862 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pediatric Brain Tumor Consortium, which has 27 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which CX 4945 is the first listed.

NCT03904862 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03904862 about?

NCT03904862 is a clinical study titled "Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery". This is a multi center, Phase I, Phase II and surgical study of the CX-4945 drug (silmitasertib sodium) for patients with recurrent SHH (Sonic Hedgehog) medulloblastoma

What is the current status of trial NCT03904862?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2019-07-25. Estimated completion is 2025-08-11.

What interventions are being tested in trial NCT03904862?

The interventions under investigation include: CX 4945 (DRUG).

Who is sponsoring clinical trial NCT03904862?

This trial is sponsored by Pediatric Brain Tumor Consortium, which has 27 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.