OHSU Knight Cancer Institute

211 total trials 35 currently recruiting 94 completed

OHSU Knight Cancer Institute sponsors 211 registered US clinical trials on ClinicalTrials.gov, 35 of them currently recruiting, and 94 completed. 5 of these trials are in Phase 3-4 (later-stage) and 114 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Acute Myeloid Leukemia, with 6 trials.

Trial Pipeline

211 total, page 1 of 5

RECRUITING Phase 2

177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer

NCT04529044

RECRUITING Phase 4

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

NCT07405086

RECRUITING Phase 1

Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation

NCT07548983

RECRUITING NA

A Tailored, Web-based Program (COMPASS) to Improve Exercise and Dietary Changes in Stage I-III Pancreatic Cancer Patients Receiving Neoadjuvant Chemotherapy

NCT07651358

RECRUITING NA

GET FIT Together: Testing a Socially Enhanced Exercise Program in Older Men With Prostate Cancer

NCT07504835

RECRUITING Early Phase 1

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

NCT07089940

RECRUITING Phase 2

Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia

NCT07228273

RECRUITING Phase 2

Intrathecal Cytarabine, Methotrexate, and Hydrocortisone for the Prevention of High-Grade Chimeric Antigen Receptor T-Cell-Associated Neurotoxicity Syndrome

NCT06895473

RECRUITING Phase 1

Glofitamab Plus Ibrutinib With Obinutuzumab for the Treatment of Patients With Mantle Cell Lymphoma, IGNITE MCL Trial

NCT06357676

RECRUITING

Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment

NCT06784167

RECRUITING Phase 2

Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML

NCT06504459

RECRUITING NA

Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

NCT06673095

RECRUITING Phase 1

Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia

NCT06357182

RECRUITING Phase 2

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer

NCT05705492

RECRUITING Phase 4

Evaluation of the Change in PSMA Expression in Prostate Cancer in Response to Hormonal Therapy

NCT05919329

RECRUITING Phase 2

Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer

NCT06067438

RECRUITING Phase 1

Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma

NCT06249191

RECRUITING NA

CREATE: Art for Children With Cancer

NCT06342453

RECRUITING Phase 1

Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors

NCT06320405

RECRUITING

Use Of Indocyanine Green In Pancreas Surgery

NCT06084013

RECRUITING Phase 2

EMBRACE: Exercising Together

NCT06049355

RECRUITING NA

Internet-Based Lifestyle Intervention to Eradicate Obese Frailty in Prostate Cancer Survivors, iLIVE

NCT06011499

RECRUITING

Developing a New Metabolic Imaging Approach (aMRI) for Evaluating Neurological Disease in Patients With Gliomas

NCT05937776

RECRUITING Phase 1

Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

NCT05943496

RECRUITING

Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer

NCT06562777

RECRUITING NA

Impact of Dietary Fiber Supplementation on Colonic Microbiome

NCT05643859

RECRUITING NA

Improving Decision-Making Encounters in Lung Cancer Using a Low-Literacy Conversation Tool

NCT05407168

RECRUITING Phase 1

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

NCT04872790

RECRUITING

Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer

NCT05081024

RECRUITING Phase 1

Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia

NCT04659616

RECRUITING NA

Identifying and Caring for Individuals With Inherited Cancer Syndrome

NCT04494945

RECRUITING Early Phase 1

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

NCT04005690

RECRUITING Phase 2

Feasibility of FMISO in Brain Tumors

NCT03649880

RECRUITING NA

War on Melanoma™ Public Health & Education Campaign

NCT04611568

RECRUITING Phase 2

Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System

NCT03270059

ACTIVE NOT RECRUITING Phase 2

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

NCT06630325

ACTIVE NOT RECRUITING

BEST-RPP Pilot: Screening for Esophageal Cancer in Rural Oregon Without an Endoscopy

NCT06335966

ACTIVE NOT RECRUITING Phase 2

Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA, IIB, or IIIA Melanoma

NCT06157099

ACTIVE NOT RECRUITING Phase 4

Evaluating Fluciclovine PET in Patients With Biochemical Recurrence of Prostate Cancer and a Negative PSMA PET

NCT05722925

ACTIVE NOT RECRUITING NA

Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation

NCT04969978

ACTIVE NOT RECRUITING Phase 1

Entrectinib in Combination With ASTX727 for the Treatment of Relapsed/Refractory TP53 Mutated Acute Myeloid Leukemia

NCT05396859

ACTIVE NOT RECRUITING Phase 1

Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

NCT05034627

ACTIVE NOT RECRUITING Phase 2

Isatuximab, Carfilzomib, and Pomalidomide for the Treatment of Relapsed or Refractory Multiple Myeloma

NCT04850599

ACTIVE NOT RECRUITING NA

Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study

NCT04993313

ACTIVE NOT RECRUITING Phase 2

NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer

NCT04539808

ACTIVE NOT RECRUITING Phase 2

mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma

NCT04251715

ACTIVE NOT RECRUITING NA

Decision Aid for the Improvement of Decision-Making in Patients With Non-small Cell Lung Cancer

NCT04946279

ACTIVE NOT RECRUITING Phase 2

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

NCT04267887

ACTIVE NOT RECRUITING Phase 1

TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer

NCT04104139

ACTIVE NOT RECRUITING Early Phase 1

Glucarpidase After High-Dose Methotrexate in Patients With Osteosarcoma

NCT03960177

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What the Pipeline for OHSU Knight Cancer Institute Shows

According to the ClinicalTrials.gov registry, OHSU Knight Cancer Institute is linked to 211 US clinical trials across every stage of research activity. Of those, 35 studies are currently recruiting, about 17% of the sponsor's indexed portfolio, and 94 are already marked complete, representing roughly 45% of the total.

The phase mix for OHSU Knight Cancer Institute reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 114 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for OHSU Knight Cancer Institute is Acute Myeloid Leukemia with 6 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.