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ClinicalTrials.gov 5 recruiting now official registry

Recurrent Prostate Carcinoma clinical trials

Every US clinical trial registered for Recurrent Prostate Carcinoma — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

30 US clinical trials · 5 currently recruiting

The research picture

Recurrent Prostate Carcinoma has 30 registered US clinical trials, 5 of them open to new participants right now — about 17% of the total.

5
recruiting participants now
17%
of trials open to enrollment
4
in Phase 3–4 (later-stage)
7
top sponsor: Jonsson Comprehensive Cancer Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 1,500 participants

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

University of Washington

NCT01050504

RECRUITING Phase 3 72 participants

REVELUTION-2: Relugolix+Abiraterone Acetate (AA) Versus Leuprolide+AA Cardiac Trial

Emory University

NCT06650579

RECRUITING Phase 2 60 participants

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

City of Hope Medical Center

NCT05722288

RECRUITING Phase 2 60 participants

Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial

City of Hope Medical Center

NCT07202247

RECRUITING Early Phase 1 30 participants

99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT04857502

ACTIVE NOT RECRUITING Phase 2 324 participants

Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial

NRG Oncology

NCT03371719

ACTIVE NOT RECRUITING Phase 2 310 participants

Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer

M.D. Anderson Cancer Center

NCT01786265

ACTIVE NOT RECRUITING Phase 3 193 participants

Multicenter Randomized Trial of 68Ga-PSMA-11 PET/CT Based SRT After Radical Prostatectomy

Jonsson Comprehensive Cancer Center

NCT03582774

ACTIVE NOT RECRUITING Phase 2 133 participants

White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Prostate CA

City of Hope Medical Center

NCT04519879

ACTIVE NOT RECRUITING Phase 2 108 participants

Bicalutamide With or Without Akt Inhibitor MK2206 in Treating Patients With Previously Treated Prostate Cancer

National Cancer Institute (NCI)

NCT01251861

ACTIVE NOT RECRUITING Phase 4 100 participants

Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer

Northwestern University

NCT03016741

ACTIVE NOT RECRUITING 92 participants

Gene Expression in Patients With Metastatic Prostate Cancer Receiving CYP-17 Inhibition Therapy

Mayo Clinic

NCT01953640

ACTIVE NOT RECRUITING Phase 2 84 participants

A Study to Evaluate Hypofractionated Proton Therapy or IMRT for Recurrent, Oligometastatic Prostate Cancer

Mayo Clinic

NCT04190446

ACTIVE NOT RECRUITING Phase 2 58 participants

Pembrolizumab in Treating Patients With Metastatic Castration Resistant Prostate Cancer Previously Treated With Enzalutamide

OHSU Knight Cancer Institute

NCT02312557

ACTIVE NOT RECRUITING Phase 1 37 participants

Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer

OHSU Knight Cancer Institute

NCT02522715

ACTIVE NOT RECRUITING Phase 2 37 participants

Abiraterone Acetate, Niclosamide, and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer

Mamta Parikh

NCT02807805

ACTIVE NOT RECRUITING Phase 1 30 participants

Prospective Exploratory Study of FAPi PET/CT in Prostate Cancer With Histopathology Validation

Jonsson Comprehensive Cancer Center

NCT04457232

ACTIVE NOT RECRUITING Phase 2 28 participants

Antiandrogen Therapy and SBRT in Treating Patients With Recurrent, Metastatic Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT03902951

ACTIVE NOT RECRUITING Phase 2 20 participants

Comparison of 18F-rhPSMA-7.3 PET/CT With and Without Furosemide in Biochemical Recurrence of Prostate Cancer

Emory University

NCT05779943

ACTIVE NOT RECRUITING Phase 2 20 participants

Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer

University of Utah

NCT03796767

ACTIVE NOT RECRUITING Phase 2 14 participants

Trametinib in Treating Patients With Progressive Metastatic Hormone-Resistant Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT02881242

COMPLETED Phase 3 1,138 participants

Gallium Ga 68-labeled PSMA-11 PET/CT in Detecting Recurrent Prostate Cancer in Patients After Initial Therapy

Jonsson Comprehensive Cancer Center

NCT02940262

COMPLETED Phase 2 112 participants

Hormone Therapy and Ipilimumab in Treating Patients With Advanced Prostate Cancer

Mayo Clinic

NCT00170157

COMPLETED Phase 2 78 participants

Tivantinib in Treating Patients With Metastatic Prostate Cancer

National Cancer Institute (NCI)

NCT01519414

COMPLETED Phase 2 50 participants

Gallium Ga 68-labeled PSMA-11 PET/CT and Fluciclovine F18 PET/CT in Imaging Participants With Recurrent Prostate Cancer After Surgery

Jonsson Comprehensive Cancer Center

NCT03515577

COMPLETED Phase 2 36 participants

Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide Therapy

OHSU Knight Cancer Institute

NCT02099864

COMPLETED Phase 2 32 participants

Biomarker-Driven Therapy With Nivolumab and Ipilimumab in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Expressing AR-V7

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT02601014

COMPLETED Phase 2 32 participants

Abiraterone Acetate in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

University of Washington

NCT01503229

COMPLETED Phase 1 10 participants

68Ga-PSMA PET/CT or PET/MRI in Evaluating Patients With Recurrent Prostate Cancer

Stanford University

NCT02488070

COMPLETED Phase 2 2 participants

Sipuleucel-T With or Without Tasquinimod in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer

Roswell Park Cancer Institute

NCT02159950

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 20
Phase 3 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent Prostate Carcinoma Trial Landscape

ClinicalTrials.gov lists 30 US studies indexed under Recurrent Prostate Carcinoma, and 5 of those are currently open to recruitment — roughly 17% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Recurrent Prostate Carcinoma shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 24 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Recurrent Prostate Carcinoma is led by Jonsson Comprehensive Cancer Center with 7 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 30 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent Prostate Carcinoma?

PlainTrial tracks 30 US clinical trials for Recurrent Prostate Carcinoma, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent Prostate Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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