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ClinicalTrials.gov 15 recruiting now early-phase tilt

Stage III Pancreatic Cancer AJCC v8: early-phase trial registry

15 of 24 indexed Stage III Pancreatic Cancer AJCC v8 trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #686 of 28,707 conditions by registered trial count.

24 US clinical trials · 15 currently recruiting · #686 of 28,707 conditions by registered trial count

Stage III Pancreatic Cancer AJCC v8: 24 US clinical trials tracked, 15 recruiting.

Stage III Pancreatic Cancer AJCC v8 is the subject of 24 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 7 of these trials.

Enrollment posture brief

Registry condition stage-iii-pancreatic-cancer-ajcc-v8

OPEN 15 | RECR 63% | LATE 2 | EARLY 21 | RANK #686 | SPON 7

Nearest open-share peer: Adolescent (63% recruiting · 16 trials)

Stage III Pancreatic Can (th…63%Aplastic Anemia37.5%Behavior37.5%Allergic Rhinitis8.3%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Stage III Pancreatic Cancer AJCC v8

Stage III Pancreatic Cancer AJCC v8 lists 15 open slots (63% of 24 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage III Pancreatic Cancer AJCC v8 on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage III Pancreatic Cancer AJCC v8 is recruiting above its size-band peers.

    15 of 24 indexed trials (62.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage III Pancreatic Cancer AJCC v8 research.

    National Cancer Institute (NCI) accounts for 7 of 24 trials (29.2%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Most Stage III Pancreatic Cancer AJCC v8 trials plan to enrol fewer than 100 people.

    Median target enrolment is 36 among the 24 trials that report a genuine target (sentinel values excluded). 22 of those (91.7%) plan for fewer than 100 participants.

  4. Stage III Pancreatic Cancer AJCC v8 research is mostly interventional.

    24 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 114Phase 27Phase 32

Open and recent trials

24 total, page 1 of 1

RECRUITING Phase 3 356 participants

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

NRG Oncology

NCT06958328

RECRUITING Phase 3 94 participants

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

SWOG Cancer Research Network

NCT06998940

RECRUITING Phase 1 92 participants

Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

National Cancer Institute (NCI)

NCT04172532

RECRUITING Early Phase 1 90 participants

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

OHSU Knight Cancer Institute

NCT04005690

RECRUITING Phase 1 52 participants

TR-002 for the Treatment of Advanced, Unresectable or Metastatic Solid Tumors and Unresectable or Metastatic, Refractory Pancreatic Adenocarcinoma

University of California, Davis

NCT07189195

RECRUITING Phase 1 49 participants

Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors

National Cancer Institute (NCI)

NCT05053971

RECRUITING Phase 1 43 participants

CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer

National Cancer Institute (NCI)

NCT05685602

RECRUITING Phase 2 40 participants

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Sameek Roychowdhury

NCT06906562

RECRUITING Phase 2 36 participants

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Emory University

NCT06423326

RECRUITING Phase 2 28 participants

Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer

City of Hope Medical Center

NCT04887805

RECRUITING Phase 2 25 participants

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

Mayo Clinic

NCT06381154

RECRUITING Phase 1 21 participants

Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer

City of Hope Medical Center

NCT04158635

RECRUITING Phase 1 19 participants

Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer

City of Hope Medical Center

NCT06454383

RECRUITING Phase 1 18 participants

Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer

National Cancer Institute (NCI)

NCT05411094

RECRUITING Early Phase 1 12 participants

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

OHSU Knight Cancer Institute

NCT07089940

ACTIVE NOT RECRUITING Phase 1 120 participants

Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer

Flemming Forsberg

NCT04821284

ACTIVE NOT RECRUITING Phase 2 88 participants

Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

National Cancer Institute (NCI)

NCT01585805

ACTIVE NOT RECRUITING Phase 1 74 participants

Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer

National Cancer Institute (NCI)

NCT03816358

ACTIVE NOT RECRUITING Phase 2 30 participants

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

OHSU Knight Cancer Institute

NCT06630325

ACTIVE NOT RECRUITING Phase 1 28 participants

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

National Cancer Institute (NCI)

NCT04514497

ACTIVE NOT RECRUITING NA 25 participants

Resistance Training Intervention to Improve Physical Function in Patients With Pancreatic Cancer Receiving Combination Chemotherapy or Have Undergone Surgery, PancStrength Study

M.D. Anderson Cancer Center

NCT04837118

ACTIVE NOT RECRUITING Phase 1 22 participants

Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (SHAPER)

University of Utah

NCT04106856

ACTIVE NOT RECRUITING Phase 1 15 participants

Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

OHSU Knight Cancer Institute

NCT05034627

COMPLETED Phase 2 13 participants

Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study

Mayo Clinic

NCT03033225

Phase Distribution

PhaseTrial count
Phase 1 14
Phase 2 7
Phase 3 2

Named interventions

Most-linked intervention names on Stage III Pancreatic Cancer AJCC v8 records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
12 trials
Biospecimen Collection Procedure
12 trials
Biopsy Procedure Procedure
6 trials
Biopsy Procedure
6 trials
Gemcitabine Drug
5 trials
Questionnaire Administration Other
4 trials
Magnetic Resonance Imaging Procedure
4 trials
Quality-of-Life Assessment Other
4 trials

US sites by state

Facility locations filed on Stage III Pancreatic Cancer AJCC v8 trials. A trial with sites in several states counts in each.

California 12 trials
Oregon 4 trials
Illinois 4 trials
Florida 4 trials
Colorado 4 trials
Arizona 4 trials
New York 3 trials
Missouri 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage III Pancreatic Cancer AJCC v8 page

24 registered trials, 15 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage III Pancreatic Cancer AJCC v8 condition card totals 24 registered trials; most-linked intervention Computed Tomography; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.