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ClinicalTrials.gov 10 recruiting now official registry

Stage II Pancreatic Cancer AJCC v8 clinical trials

10 of 17 indexed Stage II Pancreatic Cancer AJCC v8 trials are currently recruiting.

17 US clinical trials · 10 currently recruiting

Stage II Pancreatic Cancer AJCC v8 is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is OHSU Knight Cancer Institute, running 3 of these trials.

The research picture

Stage II Pancreatic Cancer AJCC v8 has 17 registered US clinical trials, 10 of them open to new participants right now, about 59% of the total.

10
recruiting participants now
59%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
3
top sponsor: OHSU Knight Cancer Institute
Phase 19Phase 26Phase 31

Active & Recent Trials

17 total, page 1 of 1

RECRUITING Phase 3 356 participants

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

NRG Oncology

NCT06958328

RECRUITING Early Phase 1 90 participants

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

OHSU Knight Cancer Institute

NCT04005690

RECRUITING NA 66 participants

Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer

University of Washington

NCT05911243

RECRUITING Phase 1 49 participants

Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors

National Cancer Institute (NCI)

NCT05053971

RECRUITING Phase 2 40 participants

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Sameek Roychowdhury

NCT06906562

RECRUITING Phase 2 36 participants

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Emory University

NCT06423326

RECRUITING Phase 2 28 participants

Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer

City of Hope Medical Center

NCT04887805

RECRUITING Phase 2 25 participants

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

Mayo Clinic

NCT06381154

RECRUITING Phase 1 18 participants

Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer

National Cancer Institute (NCI)

NCT05411094

RECRUITING Early Phase 1 12 participants

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

OHSU Knight Cancer Institute

NCT07089940

ACTIVE NOT RECRUITING Phase 1 120 participants

Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer

Flemming Forsberg

NCT04821284

ACTIVE NOT RECRUITING Phase 1 74 participants

Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer

National Cancer Institute (NCI)

NCT03816358

ACTIVE NOT RECRUITING Phase 2 39 participants

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

M.D. Anderson Cancer Center

NCT02983578

ACTIVE NOT RECRUITING Phase 1 22 participants

Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (SHAPER)

University of Utah

NCT04106856

ACTIVE NOT RECRUITING Phase 1 20 participants

A Study to Determine if the Drug, Pyrvinium Pamoate, is Safe and Tolerable in Patients With Pancreatic Cancer

Thomas Jefferson University

NCT05055323

ACTIVE NOT RECRUITING Phase 1 15 participants

Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

OHSU Knight Cancer Institute

NCT05034627

COMPLETED Phase 2 13 participants

Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study

Mayo Clinic

NCT03033225

Phase Distribution

PhaseTrial count
Phase 1 9
Phase 2 6
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Stage II Pancreatic Cancer AJCC v8 Trial Landscape

17 indexed Stage II Pancreatic Cancer AJCC v8 studies · 10 recruiting (59%).

Phase mix: 1 late (III/IV) vs 15 early (I/II).

Top sponsor: OHSU Knight Cancer Institute (3 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Stage II Pancreatic Cancer AJCC v8?

PlainTrial tracks 17 US clinical trials for Stage II Pancreatic Cancer AJCC v8, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stage II Pancreatic Cancer AJCC v8?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.