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NCT06026514 · ClinicalTrials.gov registry record · Phase 1

Phase I Safety Study of B/HPIV3/S-6P Vaccine Via Nasal Spray in Adults

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
27
Enrollment target

NCT06026514: Completed Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT06026514 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 27 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06026514, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
27 participants
Enrollment target

Study Summary

This Phase 1 clinical trial will evaluate the safety and immunogenicity of an intranasal vaccine candidate, a recombinant, live-attenuated, bovine/human parainfluenza virus vector vaccine expressing the 6-P prefusion-stabilized version of the SARS-CoV-2 spike protein.

Primary Outcome

Summary and line listing of individual clinical solicited of the frequency of solicited AEs

Interventions

  • BIOLOGICAL B/HPIV3/S-6P

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2023-09-18
Est. Completion 2025-06-30
Phase Phase 1

What the finished NCT06026514 record still lists

NCT06026514 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (55% lower).

The record links to 0 conditions, and to 1 intervention - of which B/HPIV3/S-6P is the first listed.

NCT06026514 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06026514 about?

NCT06026514 is a clinical study titled "Phase I Safety Study of B/HPIV3/S-6P Vaccine Via Nasal Spray in Adults". This Phase 1 clinical trial will evaluate the safety and immunogenicity of an intranasal vaccine candidate, a recombinant, live-attenuated, bovine/human parainfluenza virus vector vaccine expressing the 6-P prefusion-stabilized version of the SARS-CoV-2 spike protein.

What is the current status of trial NCT06026514?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2023-09-18. Estimated completion is 2025-06-30.

What interventions are being tested in trial NCT06026514?

The interventions under investigation include: B/HPIV3/S-6P (BIOLOGICAL).

Who is sponsoring clinical trial NCT06026514?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06026514's enrollment target sits among peer trials

27 1463rd of 2000 higher than 519 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06026514, the US trial registry maintained by the National Library of Medicine. NCT06026514 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.