National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 25 of 41

COMPLETED

Antiviral Therapy and HIV in the Female Genital Tract

NCT00067106

COMPLETED

Long-term Follow-up of HIV Infected Patients Identified During Early Infection

NCT00086372

COMPLETED Phase 1

Dressing Preparations for Smallpox

NCT00063856

COMPLETED Phase 2

Prevention of GBS Colonization Via Immunity

NCT00128219

COMPLETED Phase 1

Pyrimethamine to Treat Autoimmune Lymphoproliferative Syndrome

NCT00065390

COMPLETED Phase 1

Anthrax-rPA: Safety, Tolerability, Immunogenicity

NCT00063843

COMPLETED

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

NCT00042289

COMPLETED Phase 1

Reducing the Risk of Transplant Rejection: Simultaneous Kidney and Bone Marrow Transplant

NCT00063817

COMPLETED Phase 1

Combined Bone Marrow and Kidney Transplant for Multiple Myeloma With Kidney Failure

NCT00062621

TERMINATED Phase 2

Improving Transplant Options of Highly Sensitized Recipients Using IGIV-C, 10%

NCT00090194

TERMINATED Phase 1

Treating Multiple Sclerosis With Sirolimus, an Immune System Suppressor

NCT00095329

COMPLETED Phase 2

Omalizumab (Xolair) and Allergy Shots For the Treatment of Seasonal Allergies

NCT00078195

COMPLETED

Analysis of Immune Responses to HIV Vaccines

NCT00068978

COMPLETED Phase 4

When to Start Anti-HIV Drugs in Patients With Opportunistic Infections

NCT00055120

COMPLETED Phase 1

Extracorporeal Photopheresis to Maintain Symptoms Remission During Steroid Withdrawal in Patients With Steroid-Dependent Crohn's Disease

NCT00056355

COMPLETED Phase 1

Evaluation of a Diabetes Vaccine in Newly Diagnosed Diabetics

NCT00057499

COMPLETED

Immune Responses to Smallpox Vaccination

NCT00325975

COMPLETED NA

Effectiveness of Adding Interleukin-2 to Anti-HIV Drugs in Patients Recently Infected With HIV

NCT00006441

COMPLETED Phase 1

Phase I/II Trial of Modified Vaccinia Virus Ankara (MVA) Vaccine Against Smallpox

NCT00053742

COMPLETED Phase 1

HIV Vaccine Designed for HIV Infected Adults Taking Anti-HIV Drugs

NCT00056758

COMPLETED

Screening HIV-Infected Patients for Vaccine Studies

NCT00051519

COMPLETED Phase 1

Safety of RG2077 in Patients With Multiple Sclerosis

NCT00076934

COMPLETED Phase 4

Alternative Dosing Strategy for Anti-HIV Drugs

NCT00059384

COMPLETED

Cause and Natural Course of Pediatric-Onset Mastocytosis

NCT00050193

COMPLETED Phase 2

Extracorporeal Photopheresis to Treat Chronic Graft-Versus-Host Disease

NCT00048789

COMPLETED Phase 3

Fuzeon (Enfuvirtide) Early Access Program for Patients With HIV-1 Infection

NCT00050856

COMPLETED Phase 1

HIV-1 Vaccine Test in Uninfected Adult Volunteers

NCT00047931

COMPLETED Phase 2

Interferon-beta1a (AVONEX) Treatment of Ulcerative Colitis

NCT00048347

COMPLETED

Blood Factors in Mastocytosis and Unexplained Anaphylaxis and Flushing

NCT00047918

COMPLETED Phase 1

Safety of and Immune System Response to an HIV Vaccine (EP HIV-1090) in HIV Infected Patients

NCT00052182

COMPLETED Phase 2

Growth Hormone to Increase Immune Function in People With HIV

NCT00071240

COMPLETED Phase 2

Expanded Dryvax Dilution Study in Previously Vaccinated Adults

NCT00050505

COMPLETED

Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) to Evaluate Autoimmune Lymphoproliferative Syndrome (ALPS) and ALPS-associated Lymphoma

NCT00068146

COMPLETED Phase 1

Phase I Trial of Smallpox Vaccine

NCT00046397

COMPLETED NA

Promoting Adherence to Anti-HIV Drug Regimens

NCT00051805

COMPLETED Phase 2

Anti-HIV Drug Regimens and Treatment-Switching Guidelines in HIV Infected Children

NCT00039741

COMPLETED

HIV Expression in Patients With Low Viral Load on Highly Active Antiretroviral Therapy (HAART)

NCT00043641

COMPLETED Phase 1

ICC-1132 - Candidate Vaccine Against P Falciparum Malaria

NCT00587249

COMPLETED Phase 1

Valganciclovir in Congenital CMV Infants

NCT00031434

TERMINATED

Assessment of Biologic Parameters in Preparation for Future Malaria Vaccine Trials in Don gu Bougou, Mali

NCT00341783

TERMINATED Phase 4

Antibody Production in Immune Disorders

NCT00023504

COMPLETED Phase 3

Using Drug Levels in the Blood to Guide Therapy in HIV Infected Patients Taking a Protease Inhibitor

NCT00041769

COMPLETED Phase 2

Daclizumab to Treat Wegener's Granulomatosis

NCT00040248

COMPLETED Phase 1

Vaccinia Virus Vaccine (APSV) in Vaccinia- Naive Subjects: PILOT

NCT00038987

COMPLETED Phase 3

Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During Pregnancy

NCT00017719

TERMINATED Phase 2

Treatment With hOKT3gamma1(Ala-Ala) in T1DM

NCT00806572

COMPLETED Phase 3

Posaconazole to Treat Invasive Fungal Infections

NCT00033982

COMPLETED Phase 2

Leprosy Skin Test Antigens Trial

NCT00128193

COMPLETED NA

Effects of Treatment Changes on Fat Wasting in the Arms and Legs of HIV Patients

NCT00028314

COMPLETED Phase 2

Treatment of Hepatitis C in Hemophilic Patients With HIV

NCT00055341

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.