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NCT00067106 · ClinicalTrials.gov registry record

Antiviral Therapy and HIV in the Female Genital Tract

A clinical trial of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
130
Enrollment target
1
Study location

NCT00067106 is a study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 130 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00067106, a study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
130 participants
Enrollment target
1
Study location

Study Summary

HIV is found in both the blood and the genital tract. This study will compare the levels and types of HIV found in the blood with the levels and types of HIV found in the female genital tract. Study hypotheses: 1) In the presence of antiretroviral therapy, viral replication within the female genital tract may lead to the development of drug resistance that is different from that of virus in the blood plasma. 2) Antiretroviral drug levels in the female genital tract may often be lower than in the blood plasma and differences in drug exposure may be associated with differences in virus replication and selection of resistant HIV variants during drug failure. 3) HIV can be recovered in vitro from cells in the female genital tract during successful therapy, and it may be genetically different from the HIV variants recovered from the blood cell latent reservoir on the same visit.

Conditions Studied

Study Locations (1)

Rhode Island

  • The Miriam Hospital - Providence

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2003-07
Est. Completion 2009-03

What the Registry Record Tells You About NCT00067106

The ClinicalTrials.gov registry entry for NCT00067106 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (71% lower). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 0 interventions.

NCT00067106 reports 1 study location spanning 1 distinct geographic area - top geographies include Rhode Island.

Frequently Asked Questions

What is clinical trial NCT00067106 about?

NCT00067106 is a clinical study titled "Antiviral Therapy and HIV in the Female Genital Tract". HIV is found in both the blood and the genital tract. This study will compare the levels and types of HIV found in the blood with the levels and types of HIV found in the female genital tract. Study hypotheses: 1) In the presence of antiretroviral therapy, viral replication within the female genita...

What is the current status of trial NCT00067106?

This trial is currently completed. The enrollment target is 130 participants. The study started on 2003-07. Estimated completion is 2009-03.

What conditions does trial NCT00067106 study?

This clinical trial studies the following conditions: HIV Infections.

Who is sponsoring clinical trial NCT00067106?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00067106 being conducted?

This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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