National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 23 of 41

COMPLETED

Elderly Influenza Vaccine Immunogenicity Substudy

NCT00170482

COMPLETED Phase 1

Vaccine Treatment for HIV-Infection

NCT00108654

COMPLETED Phase 1

Experimental Vaccine for Malaria

NCT00114010

COMPLETED Phase 2

Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected Adults

NCT00119379

COMPLETED Phase 3

A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes

NCT00076232

COMPLETED Phase 1

Safety of Interleukin-7 in HIV Infected People Currently Taking Anti-HIV Drugs

NCT00099671

COMPLETED

Tuberculosis Immunity in Children

NCT00170638

COMPLETED Phase 2

Eldery High Dose TIV 2005

NCT00115531

COMPLETED

Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

NCT00119405

COMPLETED Phase 1

Vaccine to Prevent West Nile Virus Disease

NCT00106769

COMPLETED

Relationship Between Fatigue and Mitochondrial Damage in Patients With HIV/AIDS

NCT00106795

COMPLETED Phase 1

Improving the Efficacy of Experimental Malaria Vaccine AMA1-C1/Alhydrogel® (Registered Trademark)

NCT00340574

COMPLETED Phase 1

PpPfs25/ISA51 and ScPvs25/ISA51 Vaccines for Malaria

NCT00295581

COMPLETED Phase 1

Inactivated Influenza A/H9N2 Vaccine With and Without MF59 Adjuvant in Ambulatory Adults

NCT00133471

COMPLETED Phase 1

Interluekin-7 to Treat HIV-Infected People Receiving Antiretroviral Treatment

NCT00105417

COMPLETED

Effects of Anti-HIV Therapy on Nervous System Function

NCT00432003

COMPLETED Phase 1

A/H5N1in Adult - Aventis

NCT00115986

COMPLETED NA

Strategies to Reduce Transmission of Antimicrobial Resistant Bacteria in Intensive Care Units (STAR*ICU) Trial

NCT00100386

TERMINATED Phase 4

Anti-D for Treating Thrombocytopenia in Adults Infected With Hepatitis C Virus With or Without HIV Co-Infection

NCT00239733

COMPLETED

Urban Environmental Factors and Childhood Asthma

NCT00114881

COMPLETED

A Study of Anal Cancer Development in HIV Infected People

NCT00107679

COMPLETED Phase 1

Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4-3'delta30) in Healthy Adults

NCT00094718

COMPLETED Phase 3

Preventing Sexual Transmission of HIV With Anti-HIV Drugs

NCT00074581

COMPLETED

Clinical and Immunological Evaluation of Children With Allergies

NCT00102570

COMPLETED Phase 1

HIV-1 Vaccine Booster in Previously Immunized Uninfected Adult Volunteers

NCT00102089

COMPLETED Phase 1

Effect of Leflunomide on T Cell Proliferation in HIV-Infected Patients

NCT00101374

COMPLETED Phase 2

Safety in Immunomodulatory Functions of Alemtuzumab (Campath) in Pediatric Kidney Transplantation Recipients

NCT00240994

COMPLETED Phase 1

Safety of and Immune Response to a Dengue Virus Vaccine (rDEN2/4delta30[ME]) in Healthy Adults

NCT00094705

COMPLETED

Collection of Blood Samples From HIV Infected People

NCT00096772

COMPLETED Phase 2

Rituximab for the Treatment of Wegener's Granulomatosis and Microscopic Polyangiitis

NCT00104299

COMPLETED Phase 2

BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in Women

NCT00074425

COMPLETED Phase 1

Phase I Study of a Vaccine for Severe Acute Respiratory Syndrome (SARS)

NCT00099463

COMPLETED Phase 2

Doxycycline to Treat Mansonella Perstans Infection in Patients With and Without Lymphatic Filariasis

NCT00340691

COMPLETED Phase 3

Fluarix Immunogenicity and Safety Trial

NCT00100399

COMPLETED Phase 1

Safety of and Immune Response to a Hepatitis B Virus Vaccine Given With a Booster (CpG7909 ODN) in HIV Infected and HIV Uninfected People

NCT00100633

COMPLETED Phase 4

Influenza Vaccine in Pediatric Transplant Subjects

NCT00133510

COMPLETED Phase 1

Safety and Activity of the Oral HIV Entry Inhibitor AMD11070 in HIV Infected Patients

NCT00089466

COMPLETED Phase 4

FLU-VACS Comparative Study in Adults

NCT00133523

COMPLETED Phase 1

Inactivated Influenza Vaccine in Infants 10-22 Weeks of Age

NCT00231920

TERMINATED Phase 3

Caspofungin Study for Fungal Infections in Adults in Critical Care Settings

NCT00095316

COMPLETED Phase 1

Use of Busulfan as Conditioning Agent for a Second Stem Cell Transplant

NCT00092937

COMPLETED

Genetic Risk Factors for Severe Asthma

NCT00090740

COMPLETED Phase 1

Treating Systemic Lupus Erythematosus (SLE) Patients With CTLA4-IgG4m (RG2077)

NCT00094380

COMPLETED Phase 1

Safety of and Immune Response to Two HIV Vaccine Formulations (rMVA-HIV and rFPV-HIV) Alone or in Combination in HIV Uninfected Adults

NCT00083603

COMPLETED NA

RSV Challenge in Healthy Adults

NCT00100373

COMPLETED Phase 1

Safety of and Immune Response to a Dengue Virus Vaccine (rDEN1delta30) in Healthy Adults

NCT00089908

TERMINATED

Acute Viral Respiratory Infections in Elderly

NCT00170495

COMPLETED Phase 1

Candidate HIV Vaccine

NCT00089531

COMPLETED Phase 1

New Challenge Pool of Norwalk Virus Inoculum

NCT00138476

COMPLETED NA

Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in Adolescents

NCT00114413

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.