National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 21 of 41

COMPLETED

An Observational Study of Childhood Food Allergy

NCT00356174

COMPLETED Phase 2

Rosiglitazone Effect on Mitochondria and Lipoatrophy

NCT00367744

COMPLETED Phase 2

Alternative Oseltamivir Dosing Strategies

NCT00334529

COMPLETED Phase 1

Withdrawal of Immunosuppression in Pediatric Liver Transplant Recipients

NCT00320606

COMPLETED Phase 1

Safety and Effectiveness of Administering an HIV Vaccine in the Groin Versus the Arm

NCT00076817

COMPLETED

Cytomegalovirus Cell-Mediated Immunity

NCT00815165

COMPLETED Phase 1

Safety of and Immune Response to a Bird Flu Virus Vaccine (H5N1) in Healthy Adults

NCT00347672

COMPLETED Phase 1

Safety of and Immune Response to a Human Parainfluenza Virus Vaccine (rHPIV3cp45) in Healthy Infants

NCT00308412

COMPLETED Phase 1

Safety of and Immune Response to a Dengue Virus Vaccine (rDEN4delta30-200,201) in Healthy Adults

NCT00270699

COMPLETED

Urine Testing to Detect Kidney Transplant Rejection

NCT00337220

COMPLETED Phase 3

Immunogenicity, Safety and Tolerability of CSL Limited Inactivated Influenza Vaccine in Adults

NCT00333398

COMPLETED

Acute HIV Infection Observational Study

NCT00296660

COMPLETED Phase 2

gB/MF59 Vaccine in Preventing Cytomegalovirus Infection in Healthy Adolescent Females

NCT00133497

TERMINATED

CMV Infection in Adolescent Males

NCT00302029

COMPLETED Phase 2

Promoting Tolerance to Common Allergens in High-Risk Children: Global Prevention of Asthma in Children (GPAC) Study

NCT00346398

COMPLETED Phase 2

Safety and Tolerability of Pegylated Interferon (PEG-IFN) Alfa-2a in HIV Infected People

NCT00078442

COMPLETED

Identifying Genetic Determinants of Eczema Herpeticum and Other Viral Infections in Individuals With Atopic Dermatitis

NCT00515047

COMPLETED Phase 2

Interferon-Induced Gene Expression in Liver Cells and Peripheral Blood Lymphocytes

NCT00324389

COMPLETED Phase 1

Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly

NCT00347555

TERMINATED Phase 1

Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease

NCT00325078

TERMINATED Phase 1

Cidofovir in Renal Transplant Recipients With BKVN

NCT00138424

COMPLETED Phase 1

Phase I Study of Vaccination Schedule of Experimental HIV Vaccines

NCT00321061

COMPLETED NA

Directly Observed Therapy for HIV Infected Adolescents

NCT00259389

COMPLETED Phase 1

Safety of and Immune Response to a DNA HIV Vaccine (pGA2/JS7) Boosted With a Modified Vaccinia HIV Vaccine (MVA/HIV62) in Healthy Adults

NCT00301184

COMPLETED Phase 1

St. Jude Open Label H5 Trial

NCT00311675

COMPLETED Phase 1

Phase I Study of Safety and Persistence of UC-781 Vaginal Microbicide

NCT00441909

COMPLETED

Bacterial Pulmonary Infection in PICU

NCT00271531

COMPLETED

Metabolic Effects of Non-Thymidine Analogue Anti-HIV Medications

NCT00433992

TERMINATED Phase 2

Treatment of Ragweed-Allergic Asthma With an Immunostimulatory Drug

NCT00318747

TERMINATED Phase 2

PsA Treatment With hOKT3γ1 (Ala-Ala)

NCT00239720

COMPLETED Phase 1

Phase I Study of West Nile Virus Vaccine

NCT00300417

COMPLETED Phase 1

H5 Vaccine Alone or With Aluminum Hydroxide in Elderly Adults

NCT00294099

COMPLETED Phase 2

Immune Response to a Therapeutic HIV Vaccine Followed by Treatment Interruption in Patients With Acute or Recent HIV Infection

NCT00183261

COMPLETED Phase 2

Rituximab in Renal Allograft Recipients Who Develop Early De Novo Anti-HLA Alloantibodies

NCT00307125

COMPLETED

T and B Cell Response to Avian Flu Vaccine

NCT00337896

COMPLETED Phase 2

Use of Infliximab for the Treatment of Pemphigus Vulgaris

NCT00283712

COMPLETED Phase 1

Safety of and Immune Response to a Malaria Vaccine (MSP1 42-C1) With or Without CPG 7909 Adjuvant

NCT00320658

COMPLETED

Noninvasive Methods to Monitor Graft Survival in Kidney Transplant Patients

NCT00308802

COMPLETED Phase 1

H5 Vaccine Alone or With Adjuvant in Healthy Adults

NCT00296634

COMPLETED Phase 1

Safety and Dose Study of Peramivir for Influenza Treatment

NCT00297050

COMPLETED

Study of Factors Involved in Resistance to Severe Malaria

NCT00368810

COMPLETED

Immune Reconstitution Syndrome in HIV-Infected Patients Taking Antiretroviral Therapy

NCT00286767

COMPLETED Phase 1

Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected Children

NCT00260078

COMPLETED Phase 1

TY800 Dose Escalation (Typhoid)

NCT00269295

COMPLETED NA

Immune System Function Following Vaccination in HIV Infected Children Taking Anti-HIV Drugs

NCT00257127

COMPLETED Phase 1

Safety of and Immune Response to Two Different HIV Vaccines, Each Followed by a Adenoviral Vaccine Boost, in HIV Uninfected Adults

NCT00270218

COMPLETED Phase 1

CVD 909 Vi Prime Boost Study

NCT00326443

COMPLETED Phase 1

H5 Adult - Chiron Study of Bird Flu Vaccine

NCT00280033

COMPLETED

Voriconazole Blood Levels and Toxicity

NCT00359541

COMPLETED

Collection of Blood From Persons With Hemoglobin and Erythrocyte Polymorphisms for Laboratory Malaria Research

NCT00277849

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.