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NCT01931007 · ClinicalTrials.gov registry record · Phase 1
Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
NCT01931007: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT01931007 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 25 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01931007, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
Study Summary
The overall goal of this study is to develop regenerative cell therapy for use in patients with osteoarthritis (OA). The primary objective of this proposal is to conduct a pilot study that assesses the safety and feasibility of using concentrated bone marrow aspirate containing MSC to treat patients with painful knee OA.
Primary Outcome
Occurrence of adverse reactions to concentrated MSCs from bone marrow aspiration injected into knee joints.
Interventions
- DRUG Sterile saline
- DRUG Autologous Bone Marrow Aspirate Concentrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2013-08 |
| Est. Completion | 2016-01 |
| Phase | Phase 1 |
What the finished NCT01931007 record still lists
NCT01931007 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% lower).
The record links to 0 conditions, and to 2 interventions - of which Sterile saline is the first listed.
NCT01931007 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01931007 about?
NCT01931007 is a clinical study titled "Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis". The overall goal of this study is to develop regenerative cell therapy for use in patients with osteoarthritis (OA). The primary objective of this proposal is to conduct a pilot study that assesses the safety and feasibility of using concentrated bone marrow aspirate containing MSC to treat patients...
What is the current status of trial NCT01931007?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2013-08. Estimated completion is 2016-01.
What interventions are being tested in trial NCT01931007?
The interventions under investigation include: Sterile saline (DRUG), Autologous Bone Marrow Aspirate Concentrate (DRUG).
Who is sponsoring clinical trial NCT01931007?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01931007's enrollment target sits among peer trials
25 1495th of 2000 higher than 481 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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