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NCT01950260 · ClinicalTrials.gov registry record · Phase 2

Early Levothyroxine Post Radioactive Iodine

A Phase 2 study, sponsored by Mayo Clinic.

Completed
Registry status
Phase 2
Development phase
61
Enrollment target

NCT01950260: Completed Phase 2 study, sponsored by Mayo Clinic.

NCT01950260 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 61 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (54% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01950260, a Phase 2 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 2
Development phase
61 participants
Enrollment target

Study Summary

The study will try to answer the question of whether early treatment with levothyroxine at 4 weeks after radioactive iodine for Graves'disease will prevent overt hypothyroidism (low thyroid hormone levels).

Primary Outcome

Incidence of overt hypothyroidism at 8 weeks post radioactive iodine treatment (RAI). Overt hypothyroidism was defined as thyroid stimulating hormone (TSH) test result \> 3.0 milliunits per liter (mIU/L) or thyroid hormone free T4 (fT4) \< 0.8 nanograms per deciliter (ng/dL). Free T4 is the portion of total T4 thyroid hormone that is available to your tissues in your bloodstream.

Interventions

  • OTHER Placebo
  • DRUG Levothyroxine

Trial Details

FieldValue
Enrollment Target 61 participants
Start Date 2013-09
Est. Completion 2017-04
Phase Phase 2
Mayo Clinic

2,844 total trials

What the finished NCT01950260 record still lists

NCT01950260 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 61 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (54% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01950260 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01950260 about?

NCT01950260 is a clinical study titled "Early Levothyroxine Post Radioactive Iodine". The study will try to answer the question of whether early treatment with levothyroxine at 4 weeks after radioactive iodine for Graves'disease will prevent overt hypothyroidism (low thyroid hormone levels).

What is the current status of trial NCT01950260?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 61 participants. The study started on 2013-09. Estimated completion is 2017-04.

What interventions are being tested in trial NCT01950260?

The interventions under investigation include: Placebo (OTHER), Levothyroxine (DRUG).

Who is sponsoring clinical trial NCT01950260?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01950260's enrollment target sits among peer trials

61 1026th of 2000 higher than 974 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01950260, the US trial registry maintained by the National Library of Medicine. NCT01950260 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.