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NCT02089217 · ClinicalTrials.gov registry record · NA
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
A NA study, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 2,486
- Enrollment target
NCT02089217: Completed NA study, sponsored by Mayo Clinic.
NCT02089217 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 2,486 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (77% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02089217, a NA study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,486 participants
- Enrollment target
Study Summary
Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will randomize patients in a 1:1 ratio to carotid stenting with embolic protection versus no stenting. Medical management will be uniform for all randomized treatment groups and will be centrally directed.
Primary Outcome
The primary outcome is the composite of stroke plus death within 44 days after randomization and ipsilateral stroke thereafter up to 4 years.
Interventions
- PROCEDURE Carotid endarterectomy (CEA)
- DEVICE Carotid Stenting (CAS)
- OTHER Intensive Medical Management - no CEA
- OTHER Intensive Medical Management - no CAS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,486 participants |
| Start Date | 2014-12-09 |
| Est. Completion | 2025-09-12 |
| Phase | NA |
What the finished NCT02089217 record still lists
NCT02089217 is an interventional study that assigns participants to a tested intervention. Its 2,486 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (77% higher).
The record links to 0 conditions, and to 4 interventions - of which Carotid endarterectomy (CEA) is the first listed.
NCT02089217 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02089217 about?
NCT02089217 is a clinical study titled "Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial". Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will ra...
What is the current status of trial NCT02089217?
This trial is currently completed. It is a NA study. The enrollment target is 2,486 participants. The study started on 2014-12-09. Estimated completion is 2025-09-12.
What interventions are being tested in trial NCT02089217?
The interventions under investigation include: Carotid endarterectomy (CEA) (PROCEDURE), Carotid Stenting (CAS) (DEVICE), Intensive Medical Management - no CEA (OTHER), Intensive Medical Management - no CAS (OTHER).
Who is sponsoring clinical trial NCT02089217?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02089217's enrollment target sits among peer trials
2,486 45th of 2000 higher than 1,956 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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