Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 36 of 57

COMPLETED NA

Comparing Manual and Neurocognitive Skills-While Sitting, Standing, Walking on a Treadmill and Using a Stepper.

NCT06240286

COMPLETED NA

Prehabilitation to Improve Functional and Clinical Outcomes in Patients With Aortic Stenosis

NCT02597985

TERMINATED NA

Bathing Additives in Pediatric Atopic Dermatitis

NCT02582788

TERMINATED

Achalasia Patient Reported Outcomes

NCT02606578

COMPLETED NA

Focal Laser Ablation of Low to Intermediate Prostate Cancer Tumors

NCT02600156

TERMINATED NA

Endoscopic Intragastric Balloon Placement for Weight Loss in Liver Transplant Waitlist Candidates

NCT02556138

COMPLETED

Reliability and Validity of Patient Reported Outcome Measures in Head and Neck Cancer

NCT02554968

COMPLETED Phase 2

The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction

NCT02554253

COMPLETED NA

Incorporating Patient Capacity Into the Clinical Landscape

NCT02390570

COMPLETED

Bone Health in Patients With Overgrowth

NCT02561182

COMPLETED NA

Transforming Non-Invasive Liver Disease Detection by MRE: The Hepatogram

NCT02565446

COMPLETED

Reducing Musculoskeletal Stresses and Work-related Injuries Among Allied Health Professionals in Surgical Care

NCT02597959

TERMINATED NA

Static vs. Articulating Antibiotic Spacer for Periprosthetic Joint Infection in Total Knee Arthroplasty

NCT02547129

TERMINATED NA

Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures

NCT02597972

TERMINATED NA

Outpatient Foley Catheter Compared to Usual Inpatient Care for Labor Induction

NCT02546193

TERMINATED Phase 2

P1101 in Treating Patients With Myelofibrosis

NCT02370329

COMPLETED NA

Comparison of Positron Emission Mammography and Contrast-enhanced Breast MRI

NCT02770586

COMPLETED

Understanding Genetic Incidental Findings in Your Family (UNIFY Study)

NCT02560896

COMPLETED Phase 1

Performance of 13C Mannitol for in Vivo Measurement of Small Intestinal Permeability

NCT02603822

COMPLETED NA

Post-parotidectomy Facial Paresis: Intraoperative and Postoperative Factors

NCT02527226

COMPLETED

Endotracheal Intubation Among the Critically Ill: HEMAIR Pilot Study

NCT02508948

COMPLETED NA

Does Pulmonary Rehabilitation Improve Frailty?

NCT02512874

COMPLETED Phase 2

Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT02312245

TERMINATED Phase 1

Lenalidomide and AT-101 in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia

NCT01003769

COMPLETED Early Phase 1

Dose Response and Receptor Selectivity of Beta-blocker Effects on Bone Metabolism

NCT02467400

COMPLETED

Pencil Beam Scanning Proton Radiotherapy for Esophageal Cancer

NCT02452021

TERMINATED NA

Intrapleural Cryotherapy for Malignant Pleural Mesothelioma

NCT02464904

COMPLETED NA

Stress Echocardiography to Identify Chemotherapy Induced Cardiotoxicity in Cancer Patients With Heart Failure Risk

NCT05950399

COMPLETED Phase 1

Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

NCT02444546

COMPLETED Phase 2

A Study of Accelerated 3 Fraction Photon,Proton or Brachytherapy for Early Invasive and Noninvasive Breast Ca

NCT02453737

TERMINATED Phase 2

Lenalidomide in Improving Immune Response to Vaccine Therapy in Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Monoclonal B Cell Lymphocytosis

NCT02309515

COMPLETED NA

Resistance Training in HFpEF

NCT02435667

COMPLETED NA

Postoperative Nasal High Flow Versus Oxygen for Positive Airway Pressure Non-Compliance Sleep Apnea Patients

NCT02485236

COMPLETED NA

Stress Management Training for School Staff

NCT02366078

COMPLETED NA

Comparative Performance of Dynamic Elastic Response Feet

NCT02542761

COMPLETED Phase 2

A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification

NCT02481258

COMPLETED

International Consortium Investigating Early Vitrectomy in Diabetic Macular Edema Patients

NCT02639507

COMPLETED NA

Analyzing IBS to Identify Biomarkers and Microbiome Signatures

NCT02419963

COMPLETED Phase 4

Neoadjuvant Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Cutaneous Stage L-lll Melanoma

NCT02451488

COMPLETED NA

Integrated Tele-monitoring and Patient-centric Health Coaching Strategy in Patients Hospitalized With Heart Failure

NCT02391987

COMPLETED Phase 4

EXPAREL® for Pain After Tonsillectomy

NCT02444533

COMPLETED

Correlation of Infliximab Levels With Outcomes in Ulcerative Colitis

NCT02438410

COMPLETED Phase 3

Pentoxifylline Treatment in Acute Pancreatitis (AP)

NCT02487225

TERMINATED NA

Prospective Study of Round Window Versus Cochleostomy Approach to CI Surgery

NCT02466763

TERMINATED Phase 3

Colchicine to Prevent Post-Pericardiotomy Syndrome and Atrial Fibrillation

NCT02177266

TERMINATED

Identification of Prognostic Biomarkers for Progression of Invasive Squamous Cell Carcinoma

NCT02549638

COMPLETED

Food Antigen in Eosinophilic Esophagitis

NCT02434705

COMPLETED

Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects

NCT02372773

COMPLETED Phase 1

Fresh Versus Frozen Stool for Fecal Transplant in Children

NCT02423967

COMPLETED NA

The Effect of Two Different Tourniquet Techniques on Peripheral IV Access Success Rates

NCT02389725

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.