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NCT02266394 · ClinicalTrials.gov registry record · Phase 1
Hypoxia and Inflammatory Injury in Human Renovascular Hypertension
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 42
- Enrollment target
NCT02266394: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT02266394 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 42 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02266394, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 42 participants
- Enrollment target
Study Summary
Current treatments for ARAS based on restoring blood flow alone have been unsuccessful at recovering kidney function. For this reason we are studying a stem cell product called "mesenchymal stem cells" or MSC. Mesenchymal stem cells (MSC) are grown from a person's own fat tissue (obtained as a fat biopsy) and infused back into the patient's own kidney. This study is also being done to determine if the MSC infusion prior to percutaneous transluminal renal angioplasty with stenting (PTRA) further enhances changes in single kidney blood flow and restoration of kidney function, as well as to assess the relationship between MSC dose and measures of kidney function.
Primary Outcome
Renal Tissue oxygenation
Interventions
- DRUG Mesenchymal stem cell
- PROCEDURE Mesenchymal stem cell delivery with stent placement
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2014-10-21 |
| Est. Completion | 2020-09-25 |
| Phase | Phase 1 |
What the finished NCT02266394 record still lists
NCT02266394 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower).
The record links to 0 conditions, and to 2 interventions - of which Mesenchymal stem cell is the first listed.
NCT02266394 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02266394 about?
NCT02266394 is a clinical study titled "Hypoxia and Inflammatory Injury in Human Renovascular Hypertension". Current treatments for ARAS based on restoring blood flow alone have been unsuccessful at recovering kidney function. For this reason we are studying a stem cell product called "mesenchymal stem cells" or MSC. Mesenchymal stem cells (MSC) are grown from a person's own fat tissue (obtained as a fat b...
What is the current status of trial NCT02266394?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 42 participants. The study started on 2014-10-21. Estimated completion is 2020-09-25.
What interventions are being tested in trial NCT02266394?
The interventions under investigation include: Mesenchymal stem cell (DRUG), Mesenchymal stem cell delivery with stent placement (PROCEDURE).
Who is sponsoring clinical trial NCT02266394?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02266394's enrollment target sits among peer trials
42 1105th of 2000 higher than 876 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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