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NCT02625428 · ClinicalTrials.gov registry record · Phase 4

IRB 14-009240, Does CEUS Positively Influence Selection of Biopsy Sites When Evaluating Transplant Kidneys?

A Phase 4 study, sponsored by Mayo Clinic.

Completed
Registry status
Phase 4
Development phase
40
Enrollment target

NCT02625428: Completed Phase 4 study, sponsored by Mayo Clinic.

NCT02625428 is a Phase 4 study that has completed, run by Mayo Clinic. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT02625428, a Phase 4 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 4
Development phase
40 participants
Enrollment target

Study Summary

This is a pilot study to investigate whether contrast-enhanced ultrasound (CEUS) may help evaluate segmental differences in renal perfusion better than Doppler Ultrasound and thus help direct the biopsy to the most abnormal part of the renal cortex. This should maximize detection and increase the odds of demonstrating the true grade/severity of the histopathological abnormality.

Primary Outcome

Number of subjects with abnormal biopsies in either the primary or secondary biopsy location, by diagnosis from a clinical pathologist

Interventions

  • DIAGNOSTIC_TEST Contrast-enhanced ultrasound (CEUS)
  • DRUG Optison
  • DIAGNOSTIC_TEST Ultrasound (US)

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2015-11
Est. Completion 2019-12
Phase Phase 4
Mayo Clinic

2,844 total trials

What the finished NCT02625428 record still lists

NCT02625428 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 3 interventions - of which Contrast-enhanced ultrasound (CEUS) is the first listed.

NCT02625428 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02625428 about?

NCT02625428 is a clinical study titled "IRB 14-009240, Does CEUS Positively Influence Selection of Biopsy Sites When Evaluating Transplant Kidneys?". This is a pilot study to investigate whether contrast-enhanced ultrasound (CEUS) may help evaluate segmental differences in renal perfusion better than Doppler Ultrasound and thus help direct the biopsy to the most abnormal part of the renal cortex. This should maximize detection and increase the od...

What is the current status of trial NCT02625428?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2015-11. Estimated completion is 2019-12.

What interventions are being tested in trial NCT02625428?

The interventions under investigation include: Contrast-enhanced ultrasound (CEUS) (DIAGNOSTIC_TEST), Optison (DRUG), Ultrasound (US) (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT02625428?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02625428's enrollment target sits among peer trials

40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02625428, the US trial registry maintained by the National Library of Medicine. NCT02625428 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.