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NCT02576249 · ClinicalTrials.gov registry record · Phase 4
Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis
A Phase 4 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 4
- Development phase
- 29
- Enrollment target
NCT02576249: Completed Phase 4 study, sponsored by Mayo Clinic.
NCT02576249 is a Phase 4 study that has completed, run by Mayo Clinic. The registered enrollment target is 29 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02576249, a Phase 4 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 29 participants
- Enrollment target
Study Summary
Corticosteroid injections are commonly used for the symptomatic treatment of knee osteoarthritis. Common practice is to inject the joint with a combination of corticosteroid and local anesthetic, with the rationale of providing longer duration pain relief with the corticosteroid and immediate, though short duration relief with the anesthetic. However, multiple in vitro and animal studies have shown that local anesthetic may be harmful to chondrocytes. Despite this data, use of intra-articular anesthetic remains widespread. Many clinicians believe incorporating the anesthetic is important because it can provide immediate pain relief and facilitate patient confidence in the treatment program. However, there is no published data to validate this reasoning. Therefore, the anesthetic has unknown clinical benefit and may have adverse effects on articular cartilage. In light of this, the investigators question the routine use of anesthetics in joint injections. The purpose of this study is to compare the effects of knee joint injections using: 1) corticosteroid with local anesthetic versus 2) corticosteroid with normal saline.
Interventions
- DRUG Normal saline
- DRUG Methylprednisolone
- DRUG Ropivacaine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2015-10 |
| Est. Completion | 2016-10 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02576249
The ClinicalTrials.gov registry entry for NCT02576249 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Normal saline is the first listed.
NCT02576249 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02576249 about?
NCT02576249 is a clinical study titled "Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis". Corticosteroid injections are commonly used for the symptomatic treatment of knee osteoarthritis. Common practice is to inject the joint with a combination of corticosteroid and local anesthetic, with the rationale of providing longer duration pain relief with the corticosteroid and immediate, thoug...
What is the current status of trial NCT02576249?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 29 participants. The study started on 2015-10. Estimated completion is 2016-10.
What interventions are being tested in trial NCT02576249?
The interventions under investigation include: Normal saline (DRUG), Methylprednisolone (DRUG), Ropivacaine (DRUG).
Who is sponsoring clinical trial NCT02576249?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
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