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NCT03308578 · ClinicalTrials.gov registry record · Phase 1
Statins and CPAP in Adipose Tissue of OSA
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 50
- Enrollment target
NCT03308578: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT03308578 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 50 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03308578, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 50 participants
- Enrollment target
Study Summary
This study is aimed at examining the alterations in adipose tissue in obstructive sleep apnea (OSA) patients in response to treatment with atorvastatin in continuation with standard treatment with continuous positive airway pressure (CPAP).
Primary Outcome
Positivity for both (p16\^IND4A and γH2AX) serves as a marker of cellular damage. Fat biopsy from the will be performed to obtain up to 1 gm of adipose tissue. These fat samples will be batched for analysis to determine the prevalence of cellular damage. Biopsy will be obtained at 3 months and 6 month follow-up.
Interventions
- DRUG Placebo oral capsule
- DRUG Atorvastatin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2018-01-08 |
| Est. Completion | 2023-12-12 |
| Phase | Phase 1 |
What the finished NCT03308578 record still lists
NCT03308578 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo oral capsule is the first listed.
NCT03308578 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03308578 about?
NCT03308578 is a clinical study titled "Statins and CPAP in Adipose Tissue of OSA". This study is aimed at examining the alterations in adipose tissue in obstructive sleep apnea (OSA) patients in response to treatment with atorvastatin in continuation with standard treatment with continuous positive airway pressure (CPAP).
What is the current status of trial NCT03308578?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2018-01-08. Estimated completion is 2023-12-12.
What interventions are being tested in trial NCT03308578?
The interventions under investigation include: Placebo oral capsule (DRUG), Atorvastatin (DRUG).
Who is sponsoring clinical trial NCT03308578?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03308578's enrollment target sits among peer trials
50 973rd of 2000 higher than 984 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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