Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 31 of 57

TERMINATED

Measuring Cell Free DNA During the Course of Treatment for Esophageal Cancer as a Marker of Response and Recurrence

NCT03108885

COMPLETED Phase 2

The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade Glioma

NCT03242824

COMPLETED Phase 4

Real-Time Myocardial Perfusion Echocardiography in the ICU

NCT03173716

COMPLETED NA

Hamstring Strain in High School Athletes

NCT03248011

COMPLETED Phase 1

Pembrolizumab and Binimetinib in Treating Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer

NCT03106415

COMPLETED

Blood Brain Barrier Differences in Patients with Brain Tumors Undergoing Surgery

NCT03071913

TERMINATED NA

Use of Intra-Operative Shear Wave Ultrasound Vibrometry for Characterization of Esophageal Malignant Tumors

NCT03211780

TERMINATED

Movement and Sensation for Advanced Prosthetic Hands

NCT03259386

COMPLETED NA

Impact of Inclusion of a Therapy Dog Visit as Part of the Fibromyalgia Treatment Program

NCT03042728

TERMINATED NA

Effect of T6 Dermatome Electrical Stimulation on Gastroduodenal Motility in Healthy Volunteers

NCT03316105

COMPLETED NA

Argus II/ORCAM Device Study

NCT03248388

COMPLETED Phase 1

Midodrine Hydrochloride in Early Sepsis

NCT03129542

TERMINATED NA

Mesenteric Sparing for the Prevention of Recurrent Crohn's Disease

NCT03172143

COMPLETED NA

Minimal Risk Registry of Endoscopic Image and Pathology Correlation for Fujiflim

NCT03440047

COMPLETED

Environmental Factors to Increase Patient Comfort During Urodynamics Testing

NCT03317340

COMPLETED Phase 1

MANP in Hypertension and Metabolic Syndrome

NCT03781739

COMPLETED NA

Efficacy of IPL Treatment of Dry Eye and Ocular Rosacea

NCT03194698

COMPLETED NA

Atrial Fibrillation Screening and Education Study

NCT03440762

COMPLETED Phase 1

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

NCT03035331

COMPLETED Phase 2

Ixekizumab in the Treatment of Bullous Pemphigoid

NCT03099538

COMPLETED Phase 2

Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer

NCT03211117

TERMINATED NA

Low Dose Computed Tomography for Lung Cancer Screening

NCT03084835

COMPLETED NA

Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD

NCT02713516

COMPLETED Phase 2

Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

NCT03132532

COMPLETED Phase 2

Ixazomib Citrate, Pomalidomide, Dexamethasone, Stem Cell Transplant in Treating Relapsed or Refractory Multiple Myeloma

NCT03202628

COMPLETED NA

Vessel Wall Imaging for Diagnosis and Monitoring of Central Nervous System (CNS) Vasculitis

NCT03166319

COMPLETED NA

Effect of Coaching on Mid-Career Physician Well-Being, Job Satisfaction, and Fulfillment

NCT03207581

COMPLETED NA

Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block

NCT03478735

COMPLETED NA

Fat Emulsion in Preventing Hypersensitivity Reactions in Patients With Cancer Receiving Carboplatin or Oxaliplatin

NCT03122886

COMPLETED NA

Decision Aids to Improve Knowledge in Patients With Prostate Cancer

NCT03182998

COMPLETED Phase 2

Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer

NCT02860000

COMPLETED Phase 3

Role of Sildenafil for Fontan Associated Liver Disease (SiFALD) Study

NCT03154476

COMPLETED

Progenitor Cells in Human Esophagus

NCT03108898

COMPLETED Phase 3

Effect of GLP-1 Receptor Agonism After Sleeve Gastrectomy

NCT03115424

COMPLETED

Natural History of Eosinophilic Esophagitis

NCT03290482

TERMINATED Phase 4

Ultrasound Evaluation of Crohn's Disease

NCT03235180

COMPLETED NA

Molecular Breast Imaging and Digital Breast Tomosynthesis in Screening Patients With Dense Breast Tissue

NCT03220893

COMPLETED

Cognitive Function After Treatment of Primary CNS Malignancy

NCT03055364

COMPLETED NA

Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma

NCT03119883

COMPLETED Phase 4

The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression.

NCT03156504

COMPLETED NA

The Impact of Professional Coaching on Early Career Academic Emergency Physicians

NCT03125330

COMPLETED Phase 2

Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study

NCT03033225

COMPLETED Phase 2

Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery

NCT03008369

COMPLETED NA

EEG Cap for Identification of Non-Convulsive Status Epilepticus

NCT03138876

TERMINATED NA

Ultrasound-Assisted Lumbar Puncture

NCT03167190

COMPLETED NA

Lavender During Intrauterine Insemination

NCT03461055

COMPLETED NA

The Relationship Between Age and Carpal Tunnel Size

NCT03294733

COMPLETED NA

AKI Prevention and Early Intervention in VAD Patients Admitted for Acute Medical Events.

NCT03236103

COMPLETED NA

Opportunistic Salpingectomy for Permanent Sterilization at the Time of Cesarean Delivery

NCT03135431

TERMINATED Phase 2

Nivolumab in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma

NCT03075553

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.